Pleuropericardial Cyst Mimicking a Metastasis of Differentiated Thyroid Carcinoma on Whole-Body Iodine-131 Scan: a Case Report

Post-therapeutic whole-body scan (WBS) with I-131 has been widely used for the follow-up of patients with well-differentiated thyroid cancer (DTC). Although the sensitivity of WBS with I-131 in detection of functioning thyroid tissues is high, its specificity is low. So, a further evaluation is requ...

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Bibliographic Details
Published in:Nuclear medicine and molecular imaging 2019, 53(5), , pp.361-365
Main Authors: Bourogianni, O., Pagonidis, K., Stathaki, M., Tsaroucha, A., Papadaki, E., Koukouraki, S.
Format: Article
Language:English
Subjects:
Cancer
Cardiology
Case Report
Case reports
Chest
Cysts
Imaging
Iodine 131
Iodine isotopes
Medical imaging
Medicine
Medicine & Public Health
Nuclear Medicine
Oncology
Orthopedics
Radiology
Thyroid cancer
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Summary:Post-therapeutic whole-body scan (WBS) with I-131 has been widely used for the follow-up of patients with well-differentiated thyroid cancer (DTC). Although the sensitivity of WBS with I-131 in detection of functioning thyroid tissues is high, its specificity is low. So, a further evaluation is required in cases of unexpected findings. The purpose of the study was to demonstrate that awareness of the potential pitfalls of WBS in DTC, knowledge of physiology and characteristics of radioiodine uptake, and correlation with other imaging modalities are needed to avoid incorrect management of patients with DTC. This is a case report of a 49-year-old woman with an unexpected area of increased I-131 uptake in the posterior lower chest, which was finally diagnosed as a pleuropericardial cyst. Due to the false-positive uptake of I-131 in the chest, an accurate interpretation of the scintigraphic findings should be made.
ISSN:1869-3474
1869-3482
DOI:10.1007/s13139-019-00604-y