Similarities of Aspects of Biological Rhythms between Major Depression and Bipolar II Disorder Compared to Bipolar I Disorder: A Finding from the Early-Onset Mood Disorder Cohort

OBJECTIVEThe biological rhythm is closely related to mood symptoms. The purpose of this study was to assess the differences in biological rhythms among subjects with mood disorder [bipolar I disorder (BD I), bipolar II disorder (BD II), major depressive disorder (MDD)] and healthy control subjects....

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Published in:Psychiatry investigation 2019, 16(11), , pp.829-835
Main Authors: Kim, Su Cheol, Cho, Chul-Hyun, Lee, Yujin, Seo, Ju Yeon, Ahn, Yong-Min, Kim, Se Joo, Ha, Tae Hyon, Cha, Boseok, Moon, Eunsoo, Park, Dong Yeon, Baek, Ji Hyun, Kang, Hee-Ju, An, Hyonggin, Lee, Heon-Jeong
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Language:English
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정신과학
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Summary:OBJECTIVEThe biological rhythm is closely related to mood symptoms. The purpose of this study was to assess the differences in biological rhythms among subjects with mood disorder [bipolar I disorder (BD I), bipolar II disorder (BD II), major depressive disorder (MDD)] and healthy control subjects. METHODSA total of 462 early-onset mood disorder subjects were recruited from nine hospitals. The controls subjects were recruited from the general population of South Korea. Subject groups and control subject were evaluated for the Korean language version of Biological Rhythms Interview of Assessment in Neuropsychiatry (K-BRIAN) at the initial evaluation. RESULTSThe mean K-BRIAN scores were 35.59 [standard deviation (SD)=13.37] for BD I, 43.05 (SD=11.85) for BD II, 43.55 (SD=12.22) for MDD, and 29.1 (SD=8.15) for the control group. In the case of mood disorders, biological rhythm disturbances were greater than that in the control group (p
ISSN:1738-3684
1976-3026
DOI:10.30773/pi.2019.0232