Comparison of Characteristics and Survival between Prospective and Retrospective Korea Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Cohort Studies

By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial...

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Published in:Infection & chemotherapy 2019, 51(4), , pp.393-398
Main Authors: Kim, Jun Hyoung, Choi, Yunsu, Song, Joon Young, Kim, Shin Woo, Kim, Sang Il, Kee, Mee Kyung, Choi, Bo Youl, Choi, Jun Yong
Format: Article
Language:English
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Brief Communication
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Summary:By comparing the data of prospectively and retrospectively enrolled cohorts, we evaluated whether the prospective cohort represented all patients in the retrospective cohort. The prospectively enrolled subjects were older and had lower CD4+ T cell counts, higher viral load. In addition, the initial antiretroviral treatment regimen of the prospective cohort consisted of less integrase strand transfer inhibitor-containing regimens. The 20-year survival rate was 51.8% in the prospective cohort and 84.6% in the retrospective cohort, respectively ( = 0.844). This study suggests the prospective cohort study may not represent all patients.
ISSN:2093-2340
2092-6448
DOI:10.3947/ic.2019.51.4.393