Risk factors associated with mortality from pneumonia among patients with pneumoconiosis

• Published in: Annals of occupational and environmental medicine 2016, 28(2), , pp.1-7
• Main Authors: Jo, Bum Seak, Lee, Jongin, Cho, YounMo, Byun, Junsu, Kim, Hyoung Ryoul, Koo, Jung Wan, Myong, Jun Pyo
• Format: Article
• Language: English
• Subjects: Bacterial pneumonia; Chronic obstructive pulmonary disease; Classification; Forecasts and trends; Hospitalization; Infections; Lung diseases; Medical prognosis; Medical records; Mortality; Patient outcomes; Patients; Physiological aspects; Pneumoconiosis; Pneumonia; Respiratory diseases; Risk factors; Spirometry; Statistical analysis; 예방의학
• ISSN: 2052-4374; 2052-4374
• DOI: 10.1186/s40557-016-0103-6

The aim of this study was to evaluate factors associated with increased risk of mortality from pneumonia among patients with pneumoconiosis. Medical records of 103 pneumoconiosis patients hospitalized for pneumonia were investigated. Seven patients who had lung cancer or other malignancy and 13 patients with insufficient medical record were excluded. Two female patients were excluded due to small number to analyze. The subjects were divided into two groups by clinical outcome of pneumonia, the deceased group and the survival group. The two groups were compared in terms of age, smoking history, episode of recent pneumonia, concomitancy of interstitial fibrosis or fungal ball infection, extent of small opacities, grade of large opacities and results of spirometry. Multiple logistic regression was applied to determine the association between these variables and mortality from pneumonia. The deceased group showed more frequent history of recent pneumonia (p = 0.006), higher prevalence of interstitial fibrosis (p = 0.007) and longer hospitalization period (p = 0.044). The proportion of subjects who had decreased FVC, less than 70 % of predicted value, was higher in the deceased group (p