Characterization of breast lesions: comparison of digital breast tomosynthesis and ultrasonography

To compare the diagnostic performance of digital breast tomosynthesis (DBT) and conventional breast ultrasound (US) to characterize breast lesions as benign or malignant. A total of 332 women, presenting for screening examinations or for breast biopsy between March and June 2012 were recruited to un...

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Bibliographic Details
Published in:Korean journal of radiology 2015, 16(2), , pp.229-238
Main Authors: Kim, Sun Ah, Chang, Jung Min, Cho, Nariya, Yi, Ann, Moon, Woo Kyung
Format: Article
Language:English
Subjects:
Adult
Aged
Asymmetry
Biopsy
Breast - pathology
Breast Imaging
Breast Neoplasms - diagnosis
Breast Neoplasms - diagnostic imaging
Breasts
Cancer
Female
Humans
Mammography
Mammography - methods
Middle Aged
Population
Radiographic Image Enhancement - methods
Retrospective Studies
ROC Curve
Sensitivity and Specificity
Ultrasonic imaging
Ultrasonography, Mammary - methods
Work stations
방사선과학
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Summary:To compare the diagnostic performance of digital breast tomosynthesis (DBT) and conventional breast ultrasound (US) to characterize breast lesions as benign or malignant. A total of 332 women, presenting for screening examinations or for breast biopsy between March and June 2012 were recruited to undergo digital mammography (DM), DBT, and breast US examination. Among them, 113 patients with 119 breast lesions depicted on DM were finally included. Three blinded radiologists performed an enriched reader study and reviewed the DBT and US images. Each reader analyzed the lesions in random order, assigned Breast Imaging Reporting and Data System (BI-RADS) descriptors, rated the images for the likelihood of malignancy (%) and made a BI-RADS final assessment. Diagnostic accuracy, as assessed by the area under the receiver operating characteristic curve, sensitivity, and specificity of DBT and US were compared. Among the 119 breast lesions depicted on DM, 75 were malignant and the remaining 44 were benign. The average diagnostic performance for characterizing breast lesions as benign or malignant in terms of area under the curve was 0.899 for DBT and 0.914 for US (p = 0.394). Mean sensitivity (97.3% vs. 98.7%, p = 0.508) and specificity (44.7% vs. 39.4%, p = 0.360) were also not significantly different. Digital breast tomosynthesis may provide similar reader lesion characterization performance to that of US for breast lesions depicted on DM.
ISSN:1229-6929
2005-8330
DOI:10.3348/kjr.2015.16.2.229