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Radiofrequency ablation of renal tumors: four-year follow-up results in 47 patients
To retrospectively evaluate the intermediate results of radiofrequency ablation (RFA) of small renal masses (SRMs). Percutaneous or laparoscopic RFA was performed on 48 renal tumors in 47 patients. The follow-up studies included a physical examination, chest radiography, creatinine level, and contra...
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Published in: | Korean journal of radiology 2012, 13(5), , pp.625-633 |
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description | To retrospectively evaluate the intermediate results of radiofrequency ablation (RFA) of small renal masses (SRMs).
Percutaneous or laparoscopic RFA was performed on 48 renal tumors in 47 patients. The follow-up studies included a physical examination, chest radiography, creatinine level, and contrast-enhanced CT or MRI. To confirm the pathologic criteria of complete ablation, 35 patients underwent a follow-up biopsy. Recurrence was defined as contrast enhancement on imaging studies after 3 months, lesion growth at subsequent imaging, or viable cancer cells on follow-up biopsy.
Technical success was achieved in 43 (89.6%) of 48 renal tumors. The mean tumor size was 2.3 cm and the mean follow-up period was 49.6 months. Repeated RFA was necessary in 5 tumors due to incomplete ablation. The overall complication rate was 35.8%, of which 96.2% were mild complications. Serum creatinine levels at 12 months after RFA did not differ from those before RFA (1.28 vs. 1.36 mg/dL). Four patients were found to have recurrence at various follow-up intervals, and distant metastasis was not found in any cases.
RFA appears to be a useful treatment for selected patients with SRMs. Our 4-year follow-up results disclose an excellent therapeutic outcome with RFA, while achieving effective local tumor control. |
doi_str_mv | 10.3348/kjr.2012.13.5.625 |
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Percutaneous or laparoscopic RFA was performed on 48 renal tumors in 47 patients. The follow-up studies included a physical examination, chest radiography, creatinine level, and contrast-enhanced CT or MRI. To confirm the pathologic criteria of complete ablation, 35 patients underwent a follow-up biopsy. Recurrence was defined as contrast enhancement on imaging studies after 3 months, lesion growth at subsequent imaging, or viable cancer cells on follow-up biopsy.
Technical success was achieved in 43 (89.6%) of 48 renal tumors. The mean tumor size was 2.3 cm and the mean follow-up period was 49.6 months. Repeated RFA was necessary in 5 tumors due to incomplete ablation. The overall complication rate was 35.8%, of which 96.2% were mild complications. Serum creatinine levels at 12 months after RFA did not differ from those before RFA (1.28 vs. 1.36 mg/dL). Four patients were found to have recurrence at various follow-up intervals, and distant metastasis was not found in any cases.
RFA appears to be a useful treatment for selected patients with SRMs. Our 4-year follow-up results disclose an excellent therapeutic outcome with RFA, while achieving effective local tumor control.</description><identifier>ISSN: 1229-6929</identifier><identifier>EISSN: 2005-8330</identifier><identifier>DOI: 10.3348/kjr.2012.13.5.625</identifier><identifier>PMID: 22977331</identifier><language>eng</language><publisher>Korea (South): The Korean Society of Radiology</publisher><subject>Ablation ; Adult ; Aged ; Biopsy ; Catheter Ablation - methods ; Contrast Media ; Female ; Follow-Up Studies ; Humans ; Kidney cancer ; Kidney Neoplasms - surgery ; Laparoscopy ; Magnetic Resonance Imaging ; Male ; Medical imaging ; Middle Aged ; Neoplasm Recurrence, Local ; Original ; Patients ; Postoperative Complications ; Radiography, Thoracic ; Reoperation ; Retrospective Studies ; Success ; Tomography, X-Ray Computed ; Treatment Outcome ; Tumors ; Ultrasonic imaging ; 방사선과학</subject><ispartof>Korean Journal of Radiology, 2012, 13(5), , pp.625-633</ispartof><rights>2012. This work is published under http://creativecommons.org/licenses/by-nc/3.0 (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2012 The Korean Society of Radiology 2012</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c460t-8398a251b3f4d9b8d99ca5c6c9c2a9d20bf87466f6106d984f60fd66e5bd0ab13</citedby><cites>FETCH-LOGICAL-c460t-8398a251b3f4d9b8d99ca5c6c9c2a9d20bf87466f6106d984f60fd66e5bd0ab13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2728254163/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2728254163?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22977331$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001704447$$DAccess content in National Research Foundation of Korea (NRF)$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Soo Dong</creatorcontrib><creatorcontrib>Yoon, Seong Guk</creatorcontrib><creatorcontrib>Sung, Gyung Tak</creatorcontrib><title>Radiofrequency ablation of renal tumors: four-year follow-up results in 47 patients</title><title>Korean journal of radiology</title><addtitle>Korean J Radiol</addtitle><description>To retrospectively evaluate the intermediate results of radiofrequency ablation (RFA) of small renal masses (SRMs).
Percutaneous or laparoscopic RFA was performed on 48 renal tumors in 47 patients. The follow-up studies included a physical examination, chest radiography, creatinine level, and contrast-enhanced CT or MRI. To confirm the pathologic criteria of complete ablation, 35 patients underwent a follow-up biopsy. Recurrence was defined as contrast enhancement on imaging studies after 3 months, lesion growth at subsequent imaging, or viable cancer cells on follow-up biopsy.
Technical success was achieved in 43 (89.6%) of 48 renal tumors. The mean tumor size was 2.3 cm and the mean follow-up period was 49.6 months. Repeated RFA was necessary in 5 tumors due to incomplete ablation. The overall complication rate was 35.8%, of which 96.2% were mild complications. Serum creatinine levels at 12 months after RFA did not differ from those before RFA (1.28 vs. 1.36 mg/dL). Four patients were found to have recurrence at various follow-up intervals, and distant metastasis was not found in any cases.
RFA appears to be a useful treatment for selected patients with SRMs. Our 4-year follow-up results disclose an excellent therapeutic outcome with RFA, while achieving effective local tumor control.</description><subject>Ablation</subject><subject>Adult</subject><subject>Aged</subject><subject>Biopsy</subject><subject>Catheter Ablation - methods</subject><subject>Contrast Media</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Kidney cancer</subject><subject>Kidney Neoplasms - surgery</subject><subject>Laparoscopy</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local</subject><subject>Original</subject><subject>Patients</subject><subject>Postoperative Complications</subject><subject>Radiography, Thoracic</subject><subject>Reoperation</subject><subject>Retrospective Studies</subject><subject>Success</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><subject>Tumors</subject><subject>Ultrasonic imaging</subject><subject>방사선과학</subject><issn>1229-6929</issn><issn>2005-8330</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNpdUV1rFDEUDaLYdfUH-CIDvvgy03xP4oNQStVCodDW55DJJDq72cmYzFT23_e2q6UVAjck59x7zj0IvSe4YYyr4-0mNxQT2hDWiEZS8QKtKMaiVozhl2hFKNW11FQfoTelbDCmGiv-Gh3Be9syRlbo-sr2QwrZ_1786PaV7aKdhzRWKVTZjzZW87JLuXyuQlpyvfc2wy3G9KdeJkCUJc6lGsaKt9UETD_O5S16FWws_t3fukY_vp7dnH6vLy6_nZ-eXNSOSzyDSK0sFaRjgfe6U73WzgonnXbU6p7iLqiWSxkkwbLXigeJQy-lF12PbUfYGn069B1zMFs3mGSHh_ozmW02J1c356YlAjwD9MsBOi3dzvcOZGYbzZSHnc37B-Lzn3H4BW1uDeNMKPlk1pQTrKrMZjcU52O0o09LMQSDGyUYnDX6-B90A6uDVRZDW6qo4EQyQJEDyuVUSvbhUQzB5j5dA-ma-3QNYUYYSBc4H566eGT8i5PdAd4GoUg</recordid><startdate>20120901</startdate><enddate>20120901</enddate><creator>Kim, Soo Dong</creator><creator>Yoon, Seong Guk</creator><creator>Sung, Gyung Tak</creator><general>The Korean Society of Radiology</general><general>대한영상의학회</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>ACYCR</scope></search><sort><creationdate>20120901</creationdate><title>Radiofrequency ablation of renal tumors: four-year follow-up results in 47 patients</title><author>Kim, Soo Dong ; Yoon, Seong Guk ; Sung, Gyung Tak</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c460t-8398a251b3f4d9b8d99ca5c6c9c2a9d20bf87466f6106d984f60fd66e5bd0ab13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Ablation</topic><topic>Adult</topic><topic>Aged</topic><topic>Biopsy</topic><topic>Catheter Ablation - methods</topic><topic>Contrast Media</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Kidney cancer</topic><topic>Kidney Neoplasms - surgery</topic><topic>Laparoscopy</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Middle Aged</topic><topic>Neoplasm Recurrence, Local</topic><topic>Original</topic><topic>Patients</topic><topic>Postoperative Complications</topic><topic>Radiography, Thoracic</topic><topic>Reoperation</topic><topic>Retrospective Studies</topic><topic>Success</topic><topic>Tomography, X-Ray Computed</topic><topic>Treatment Outcome</topic><topic>Tumors</topic><topic>Ultrasonic imaging</topic><topic>방사선과학</topic><toplevel>online_resources</toplevel><creatorcontrib>Kim, Soo Dong</creatorcontrib><creatorcontrib>Yoon, Seong Guk</creatorcontrib><creatorcontrib>Sung, Gyung Tak</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Databases</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Korean Citation Index</collection><jtitle>Korean journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Soo Dong</au><au>Yoon, Seong Guk</au><au>Sung, Gyung Tak</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Radiofrequency ablation of renal tumors: four-year follow-up results in 47 patients</atitle><jtitle>Korean journal of radiology</jtitle><addtitle>Korean J Radiol</addtitle><date>2012-09-01</date><risdate>2012</risdate><volume>13</volume><issue>5</issue><spage>625</spage><epage>633</epage><pages>625-633</pages><issn>1229-6929</issn><eissn>2005-8330</eissn><abstract>To retrospectively evaluate the intermediate results of radiofrequency ablation (RFA) of small renal masses (SRMs).
Percutaneous or laparoscopic RFA was performed on 48 renal tumors in 47 patients. The follow-up studies included a physical examination, chest radiography, creatinine level, and contrast-enhanced CT or MRI. To confirm the pathologic criteria of complete ablation, 35 patients underwent a follow-up biopsy. Recurrence was defined as contrast enhancement on imaging studies after 3 months, lesion growth at subsequent imaging, or viable cancer cells on follow-up biopsy.
Technical success was achieved in 43 (89.6%) of 48 renal tumors. The mean tumor size was 2.3 cm and the mean follow-up period was 49.6 months. Repeated RFA was necessary in 5 tumors due to incomplete ablation. The overall complication rate was 35.8%, of which 96.2% were mild complications. Serum creatinine levels at 12 months after RFA did not differ from those before RFA (1.28 vs. 1.36 mg/dL). Four patients were found to have recurrence at various follow-up intervals, and distant metastasis was not found in any cases.
RFA appears to be a useful treatment for selected patients with SRMs. Our 4-year follow-up results disclose an excellent therapeutic outcome with RFA, while achieving effective local tumor control.</abstract><cop>Korea (South)</cop><pub>The Korean Society of Radiology</pub><pmid>22977331</pmid><doi>10.3348/kjr.2012.13.5.625</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Ablation Adult Aged Biopsy Catheter Ablation - methods Contrast Media Female Follow-Up Studies Humans Kidney cancer Kidney Neoplasms - surgery Laparoscopy Magnetic Resonance Imaging Male Medical imaging Middle Aged Neoplasm Recurrence, Local Original Patients Postoperative Complications Radiography, Thoracic Reoperation Retrospective Studies Success Tomography, X-Ray Computed Treatment Outcome Tumors Ultrasonic imaging 방사선과학 |
title | Radiofrequency ablation of renal tumors: four-year follow-up results in 47 patients |
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