Follow-up result afters negative findings on unenhanced hepatic MR imaging for hepatic metastasis from rectal cancer

• Published in: Korean journal of radiology 2004, 5(4), , pp.225-230
• Main Authors: Lim, Joon Seok, Kim, Myeong-Jin, Lee, Kang Young, Kim, Nam Kyu, Choi, Jin-Sub, Kim, Joo Hee, Oh, Young Taik, Kim, Won Ho, Kim, Ki Whang
• Format: Article
• Language: English
• Subjects: Adenocarcinoma - diagnosis; Adenocarcinoma - diagnostic imaging; Adenocarcinoma - secondary; Adenocarcinoma - surgery; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor - blood; Carcinoembryonic Antigen - blood; Digestive System Surgical Procedures; False Negative Reactions; Female; Follow-Up Studies; Humans; Liver Neoplasms - diagnosis; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Predictive Value of Tests; Rectal Neoplasms - pathology; Retrospective Studies; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome; 방사선과학
• ISSN: 1229-6929; 2005-8330
• DOI: 10.3348/kjr.2004.5.4.225

To assess the follow-up results after negative findings on unenhanced hepatic MR imaging in rectal cancer patients who have undergone locally curative surgery. From all pertinent imaging reports and medical records, we selected 255 patients who had negative results on unenhanced hepatic MR imaging. When selecting patients who had undergone curative resection, the following patients were excluded from the study: 1) patients in whom extrahepatic metastases were detected on preoperative staging work-ups, 2) patients in whom the surgery was judged to be non-curative due to peritoneal seeding or local aggressiveness. Cases with follow-up periods of less than 18 months were also excluded, as these cases were considered insufficient to confirm the negative outcomes. Thus, a total of 149 patients were ultimately enrolled in our study. The follow-up results of unenhanced MR imagings were assessed according to the assumption that the newly developed hepatic metastases had been false-negative lesions on preoperative MR image. During a median follow-up period of 29.3 months, 25 hepatic metastases were detected in 13 patients (8.7%), which indicated a negative predictive value of 91.3%. Unenhanced hepatic MR imaging provides a high negative predictive value with regard to the detection of hepatic metastasis in the preoperative evaluation of rectal cancer.