Total intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case report

A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patient...

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Bibliographic Details
Published in:Korean journal of anesthesiology 2010, 58(4), , pp.409-412
Main Authors: Park, Jin Suk, Baek, Chong Wha, Kang, Hyun, Cha, Su Man, Park, Jung Won, Jung, Yong Hun, Woo, Young-Cheol
Format: Article
Language:English
Subjects:
atracurium
Case Report
general anesthesia
melas syndrome
propofol
remifentanil
tiva
마취과학
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Summary:A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome.
ISSN:2005-6419
2005-7563
DOI:10.4097/kjae.2010.58.4.409