Validation of the Korean Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale

• Published in: Journal of clinical neurology (Seoul, Korea) 2020, 16(2), , pp.245-253
• Main Authors: Choi, Ji Hyun, Lee, Jee Young, Cho, Jin Whan, Ko, Seong Beom, Ahn, Tae Beom, Kim, Sang Jin, Cheon, Sang Myung, Kim, Joong Seok, Kim, Yoon Joong, Ma, Hyeo Il, Baik, Jong Sam, Lee, Phil Hyu, Chung, Sun Ju, Kim, Jong Min, Song, In Uk, Kim, Han Joon, Sung, Young Hee, Kwon, Do Young, Lee, Jae Hyeok, Kim, Ji Young, Kim, Ji Sun, Yun, Ji Young, Kim, Hee Jin, Hong, Jin Yong, Kim, Mi Jung, Youn, Jinyoung, Kim, Ji Seon, Oh, Eung Seok, Yang, Hui Jun, Yoon, Won Tae, You, Sooyeoun, Kwon, Kyum Yil, Park, Hyung Eun, Lee, Su Yun, Kim, Younsoo, Kim, Hee Tae, Park, Mee Young
• Format: Article
• Language: English
• Subjects: Original; 신경과학
• ISSN: 1738-6586; 2005-5013
• DOI: 10.3988/jcn.2020.16.2.245

Impulse-control disorder is an important nonmotor symptom of Parkinson's disease (PD) that can lead to financial and social problems, and be related to a poor quality of life. A nationwide multicenter prospective study was performed with the aim of validating the Korean Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease Rating Scale (K-QUIP-RS). The K-QUIP-RS was constructed using forward and backward translation, and pretesting of the prefinal version. PD patients on stable medical condition were recruited from 27 movement-disorder clinics. Participants were assessed using the K-QUIP-RS and evaluated for parkinsonian motor and nonmotor statuses and for PD-related quality of life using a predefined evaluation battery. The test-retest reliability of the K-QUIP-RS was assessed over an interval of 10-14 days, and correlations between the KQUIP-RS and other clinical scales were analyzed. This study enrolled 136 patients. The internal consistency of the K-QUIP-RS was indicated by a Cronbach's α coefficient of 0.846, as was the test-retest reliability by a Guttman split-half coefficient of 0.808. The total K-QUIP-RS score was positively correlated with the scores for depression and motivation items on the Unified PD Rating Scale (UPDRS), Montgomery-Asberg Depression Scale, and Rapid-Eye-Movement Sleep-Behavior-Disorders Questionnaire. The total K-QUIP-RS score was also correlated with the scores on part II of the UPDRS and the PD Quality of Life-39 questionnaire, and the dopaminergic medication dose. The K-QUIP-RS appears to be a reliable assessment tool for impulse-control and related behavioral disturbances in the Korean PD population.