Posterior subtenon triamcinolone acetonide in gas-filled eyes as an adjunctive treatment for complicated proliferative diabetic retinopathy

To evaluate the effect of adjunctive subtenon injection of triamcinolone acetonide (TA) in gas-filled eyes after vitrectomy for complicated proliferative diabetic retinopathy (PDR). This nonrandomized comparative study included 27 patients (27 eyes) who underwent pars plana vitrectomy and gas tampon...

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Bibliographic Details
Published in:Korean journal of ophthalmology 2013, 27(1), , pp.28-33
Main Authors: Lee, Yongeun, Kang, Seungbum, Park, Young-Hoon
Format: Article
Language:English
Subjects:
Diabetic Retinopathy - complications
Diabetic Retinopathy - therapy
Female
Gases
Glucocorticoids - administration & dosage
Humans
Injections
Male
Middle Aged
Original
Tenon Capsule
Treatment Outcome
Triamcinolone Acetonide - administration & dosage
Visual Acuity
Vitrectomy - methods
Vitreoretinopathy, Proliferative - etiology
Vitreoretinopathy, Proliferative - therapy
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Summary:To evaluate the effect of adjunctive subtenon injection of triamcinolone acetonide (TA) in gas-filled eyes after vitrectomy for complicated proliferative diabetic retinopathy (PDR). This nonrandomized comparative study included 27 patients (27 eyes) who underwent pars plana vitrectomy and gas tamponade for treatment of PDR with tractional or combined tractional-rhegmatogenous retinal detachment and who received subtenon injection of TA (40 mg) at the end of surgery. The study group was compared with the control group (29 eyes), which was matched with the study group for preoperative and intraoperative parameters, but underwent pars plana vitrectomy and gas tamponade without a subtenon injection of TA. Retinal reattachments without reoperation were achieved in 25 eyes (92.6%) and 26 eyes (89.7%) at 6 months (p = 1.000) in the study and control groups, respectively. The study group and the control group did not differ significantly in the frequency of postoperative proliferative vitreoretinopathy, retinal redetachment rate, reoperation rate, macular pucker formation, postoperative vitreous hemorrhage, gain in visual acuity, intraocular pressure, and intraocular inflammation (p > 0.05). The clinical results of pars plana vitrectomy for complicated PDR are not improved significantly by an adjunctive subtenon TA injection in gas-filled eyes.
ISSN:1011-8942
2092-9382
DOI:10.3341/kjo.2013.27.1.28