The clinical characteristics of optic neuritis in Korean children

To study the clinical characteristics of optic neuritis in Korean children. A retrospective review of the medical charts of 20 patients who were diagnosed with optic neuritis before age 10 was conducted in this study. Data were collected on the demographics, clinical features, use of intravenous cor...

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Bibliographic Details
Published in:Korean journal of ophthalmology 2011, 25(2), , pp.116-120
Main Authors: Jo, Dong Hyun, Kim, Seong-Joon, Chae, Jong Hee, Yu, Young Suk
Format: Article
Language:English
Subjects:
Age Distribution
Child
Child, Preschool
Female
Humans
Incidence
Magnetic Resonance Imaging - methods
Male
Optic Neuritis - diagnosis
Optic Neuritis - epidemiology
Optic Neuritis - physiopathology
Original
Republic of Korea - epidemiology
Retrospective Studies
Severity of Illness Index
Visual Acuity
안과학
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Summary:To study the clinical characteristics of optic neuritis in Korean children. A retrospective review of the medical charts of 20 patients who were diagnosed with optic neuritis before age 10 was conducted in this study. Data were collected on the demographics, clinical features, use of intravenous corticosteroids, neuroimaging, and diagnosis of multiple sclerosis. The mean age at diagnosis was 6.5 ± 1.8 years (range, 3 to 9 years). Seventeen patients (85%) were female, and 13 patients (65%) exhibited bilateral diseases. Visual acuity had decreased to ≤20 / 200 in 16 of the 20 patients, and recovered to ≥20 / 40 in 16 of the 20 patients. The mean duration between the worst visual acuity and 20 / 40 was 2.30 ± 2.91 months. Intravenous corticosteroid treatment was performed in 15 patients and exerted a beneficial effect on the visual outcomes. Disc swelling was observed in 75.8% of the affected eyes. Multiple sclerosis was diagnosed in five patients with a mean follow-up period of 21.9 ± 20.3 months. The presence of lesions in brain magnetic resonance images was identified as the most significant factor with regards to the occurrence of multiple sclerosis. In children with optic neuritis, a profound decrease in initial visual acuity and rapid recovery of visual acuity were confirmed. Corticosteroid treatment resulted in a beneficial effect on visual outcomes, but had no effect on the risk of multiple sclerosis.
ISSN:1011-8942
2092-9382
DOI:10.3341/kjo.2011.25.2.116