Hepatoid carcinoma of the ovary without staining for alpha-fetoprotein

Primary hepatoid carcinoma of the ovary (HCO) is a rare type of ovarian tumor that resembles hepatocellular carcinoma both histologically and immunohistochemically in its staining for alpha-fetoprotein (AFP). We describe a 51-year-old woman who presented to our hospital complaining of abdominal pain...

Full description

Saved in:
Bibliographic Details
Published in:Obstetrics & gynecology science 2013, 56(01), 607, pp.41-44
Main Authors: Sung, Ji-Hee, Kim, Tae Hyun, Park, Hyang Gi, Kim, Min Ji, Kim, Byoung-Gie, Kim, Tae-Joong, Bae, Duk-Soo
Format: Article
Language:English
Subjects:
Case Report
산부인과학
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Primary hepatoid carcinoma of the ovary (HCO) is a rare type of ovarian tumor that resembles hepatocellular carcinoma both histologically and immunohistochemically in its staining for alpha-fetoprotein (AFP). We describe a 51-year-old woman who presented to our hospital complaining of abdominal pain. Computed tomography scan revealed a large tumor in the pelvis. She underwent total hysterectomy and bilateral salpingo-oophorectomy with tumorectomy. A right ovarian mass measuring 9×8×6 cm was found. Histological diagnosis was hepatoid carcinoma of the right ovary. But, immunohistochemically, tumor cells were not immunoreactive for AFP and there was no elevation of serum AFP level. This is the first report of an ovarian carcinoma with typical histologic features of HCO with negative staining for AFP and normal level of serum AFP in the world.
ISSN:2287-8572
2287-8580
DOI:10.5468/OGS.2013.56.1.41