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Preparation of Furfuryl-fish gelatin (F-f.gel) cured using visible-light and its application as an anti-adhesion agent

Adhesions occurring on a variety tissues and operation sites are a serious side effect of surgery and may require additional surgery for removal. Therefore, Furfuryl-fish gelatin (F-f.gel) was synthesized by introducing a furan ring to fish gelatin for application as an anti-adhesion agent. F-f.gel...

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Published in:Macromolecular research 2012, 20(8), , pp.842-846
Main Authors: Park, Shin-Hye, Seo, Si-Yoong, Lee, Hyung-Jae, Na, Ha-Na, Lee, Jea-Woo, Woo, Hee-Dong, Son, Tae-Il
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description Adhesions occurring on a variety tissues and operation sites are a serious side effect of surgery and may require additional surgery for removal. Therefore, Furfuryl-fish gelatin (F-f.gel) was synthesized by introducing a furan ring to fish gelatin for application as an anti-adhesion agent. F-f.gel was cured by visible-light irradiation, which changed the material from a solution to a film. The prepared F-f.gel was characterized by proton nuclear magnetic resonance spectroscopy ( 1 H NMR), substitution ratio, gel permeation chromatography (GPC), methyl thiazolyl tetrazolium (MTT) assay, and tests for measuring photo immobilization, water contact angle (WCA), and cell attachment. The results showed that F-f.gel was effective as an anti-adhesion agent.
doi_str_mv 10.1007/s13233-012-0128-9
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source Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List
subjects Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Complex Fluids and Microfluidics
Nanochemistry
Nanotechnology
Physical Chemistry
Polymer Sciences
Soft and Granular Matter
고분자공학
title Preparation of Furfuryl-fish gelatin (F-f.gel) cured using visible-light and its application as an anti-adhesion agent
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