Chemical functionalization and stabilization of type I collagen with organic tanning agents

We investigated the interactions between selected organic tanning agents and type I fibrillar collagen as a model fibrillar substrate to enable the fast direct evaluation and validation of interpretations of tanning activity. Type I fibrillar collagen (1%) as gel was used as substrate of tanning and...

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Bibliographic Details
Published in:The Korean journal of chemical engineering 2015, 32(2), 179, pp.354-361
Main Authors: Albu, Madalina Georgiana, Deselnicu, Viorica, Ioannidis, Ioannis, Deselnicu, Dana, Chelaru, Ciprian
Format: Article
Language:English
Subjects:
Biotechnology
Catalysis
Chemistry
Chemistry and Materials Science
Industrial Chemistry
Industrial Chemistry/Chemical Engineering
Materials Science
Polymer
화학공학
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Summary:We investigated the interactions between selected organic tanning agents and type I fibrillar collagen as a model fibrillar substrate to enable the fast direct evaluation and validation of interpretations of tanning activity. Type I fibrillar collagen (1%) as gel was used as substrate of tanning and tannic acid, resorcinol- and melamine-formaldehyde and their combination at three concentrations as crosslinking agents (tannins). To evaluate the stability of collagen during tanning, the crosslinked gels at 2.8, 4.5 and 9.0 pHs were freeze-dried as discs which were characterized by FT-IR, shrinkage temperature, enzymatic degradation and optical microscopy, and the results were validated by statistical analyses. The best stability was given by combinations between resorcinol- and melamine-formaldehyde at isoelectric pH.
ISSN:0256-1115
1975-7220
DOI:10.1007/s11814-014-0197-x