Quercetin 7-O-Glutamate Potentiates Staphylococcus aureus to Fluoroquinolone Antibiotics

The quercetin conjugate Q‐7‐O‐Glu (5) showed inhibition of NorA efflux pump and thereby potentiation of antibacterial activity of various antibiotics against S. aureus. In particular, upon combination with 5, the fluoroquinolone antibiotics (ciprofloxacin) showed 4‐times enhanced antibacterial activ...

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Published in:Bulletin of the Korean Chemical Society 2016, 37(9), , pp.1515-1517
Main Authors: Park, Kwang-Su, Choo, Hyunah, Kim, Mi Kyoung, Chong, Youhoon
Format: Article
Language:English
Subjects:
Efflux pump inhibitor
Fluoroquinolone
Quercetin conjugate
Staphylococcus aureus
화학
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description The quercetin conjugate Q‐7‐O‐Glu (5) showed inhibition of NorA efflux pump and thereby potentiation of antibacterial activity of various antibiotics against S. aureus. In particular, upon combination with 5, the fluoroquinolone antibiotics (ciprofloxacin) showed 4‐times enhanced antibacterial activity against S. aureus.
doi_str_mv 10.1002/bkcs.10901
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identifier ISSN: 1229-5949
ispartof Bulletin of the Korean Chemical Society, 2016, 37(9), , pp.1515-1517
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1229-5949
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source Wiley-Blackwell Read & Publish Collection
subjects Efflux pump inhibitor
Fluoroquinolone
Quercetin conjugate
Staphylococcus aureus
화학
title Quercetin 7-O-Glutamate Potentiates Staphylococcus aureus to Fluoroquinolone Antibiotics
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