Protein Tyrosine Phosphatase 1B Inhibitors: Heterocyclic Carboxylic Acids

Several series of compounds (benzoic acids, pyrazolecarboxylic acids, phenoxyacetic acids, and quinolinoxyacetic acids) were prepared and evaluated for their inhibitory activity against PTP-1B. Several compounds showed submicromolar inhibitory activity.

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Published in:Bulletin of the Korean Chemical Society 2003, 24(10), , pp.1455-1464
Main Authors: Cho, Sung-Yun, Ahn, Jin-Hee, Ha, Jae-Du, Kang, Seung-Kyu, Baek, Ji-Yoen, Han, Sang-Sub, Shin, Eun-Young, Kim, Sung-Soo, Kim, Kwang-Rok, Cheon, Hyae-Gyeong, Choi, Joong-Kwon
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container_issue 10
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container_title Bulletin of the Korean Chemical Society
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creator Cho, Sung-Yun
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Kim, Kwang-Rok
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description Several series of compounds (benzoic acids, pyrazolecarboxylic acids, phenoxyacetic acids, and quinolinoxyacetic acids) were prepared and evaluated for their inhibitory activity against PTP-1B. Several compounds showed submicromolar inhibitory activity.
doi_str_mv 10.5012/bkcs.2003.24.10.1455
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title Protein Tyrosine Phosphatase 1B Inhibitors: Heterocyclic Carboxylic Acids
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