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The Inhibitory Effect of Prunioside A Acyl Derivativeson NO Production in RAW 264.7 Cell

Prunioside A is a unique, highly oxidized monoterpene glycoside isolated from the methanol extract of Spiraea prunifolia var. Simpliciflora's root. The ester derivatives were synthesized from the hydrolyzed compounds of prunioside A by β-glucosidase. The derivatives showed suppressive effects o...

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Bibliographic Details
Published in:Bulletin of the Korean Chemical Society 2004, 25(10), , pp.1555-1558
Main Authors: 이우일, Byung Hee Kim, Young Hang Lee, 최한길, 전병훈, 장선일, 김영준, Hun Taeg Chung, 김영순, 채규윤
Format: Article
Language:English
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Summary:Prunioside A is a unique, highly oxidized monoterpene glycoside isolated from the methanol extract of Spiraea prunifolia var. Simpliciflora's root. The ester derivatives were synthesized from the hydrolyzed compounds of prunioside A by β-glucosidase. The derivatives showed suppressive effects on the generation of nitric oxide in murine machrophage-like RAW 264.7 cells stimulated by lipopolysaccharide and interferon- γ. KCI Citation Count: 2
ISSN:0253-2964
1229-5949