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Giant malignant insulinoma

Insulinomas are the most common pancreatic neuroendocrine tumors. Most insulinomas are benign, small, intrapancreatic solid tumors and only large tumors have a tendency for malignancy. Most patients present with symptoms of hypoglycemia that are relieved with the administration of glucose. We herein...

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Bibliographic Details
Published in:Annals of surgical treatment and research 2015, 88(5), , pp.289-293
Main Authors: Karavias, Dimitrios, Habeos, Ioannis, Maroulis, Ioannis, Kalogeropoulou, Christina, Tsamandas, Athanasios, Chaveles, Ioannis, Karavias, Dionissios
Format: Article
Language:English
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Summary:Insulinomas are the most common pancreatic neuroendocrine tumors. Most insulinomas are benign, small, intrapancreatic solid tumors and only large tumors have a tendency for malignancy. Most patients present with symptoms of hypoglycemia that are relieved with the administration of glucose. We herein present the case of a 75-year-old woman who presented with an acute hypoglycemic episode. Subsequent laboratory and radiological studies established the diagnosis of a 17-cm malignant insulinoma, with local invasion to the left kidney, lymph node metastasis, and hepatic metastases. Patient symptoms, diagnostic and imaging work-up and surgical management of both the primary and the metastatic disease are reviewed.
ISSN:2288-6575
2288-6796
DOI:10.4174/astr.2015.88.5.289