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Characterization of sphere-forming HCT116 clones by whole RNA sequencing

To determine CD133(+) cells defined as cancer stem cells (CSCs) in colon cancer, we examined whether CD133(+) clones in HCT116 demonstrate known features of CSCs like sphere-forming ability, chemodrug-resistance, and metastatic potential. Magnetic cell isolation and cell separation demonstrated that

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Bibliographic Details
Published in:Annals of surgical treatment and research 2016, 90(4), , pp.183-193
Main Authors: Chung, Eunkyung, Oh, Inkyung, Lee, Kil Yeon
Format: Article
Language:English
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Summary:To determine CD133(+) cells defined as cancer stem cells (CSCs) in colon cancer, we examined whether CD133(+) clones in HCT116 demonstrate known features of CSCs like sphere-forming ability, chemodrug-resistance, and metastatic potential. Magnetic cell isolation and cell separation demonstrated that
ISSN:2288-6575
2288-6796
DOI:10.4174/astr.2016.90.4.183