Insecticidal activities of Ruta chalepensis leavesisolated constituent and structure-relationships of its analogues against Sitophilus oryzae

• Published in: Applied biological chemistry 2013, 56(5), , pp.591-596
• Main Authors: Ju-Hyun, Jeon, Min-Gi, Kim, Lee, Hoi-Seon
• Format: Article
• Language: English
• Subjects: Adults; Aldehydes; Chloroform; Chromatography; Constituents; Derivatives; Food production; Insects; Pests; Quinoline; Ruta chalepensis; Sitophilus oryzae; Stored products; Toxicity; 농학
• ISSN: 2468-0834; 2468-0842
• DOI: 10.1007/s13765-013-3215-5

The insecticidal activities of active component isolated from Ruta chalepensis L. (Rutales: Rutaceae) leaves and its derivatives were examined using fumigant and contact toxicity methods against rice weevil, Sitophilus oryaze L. (Coleoptera: Curculionidae) adults. Administering the chloroform fraction of the methanol extract resulted in 87.7% mortality at 1.02 mg/cm2 against S. oryzae adults, using a fumigant method. The insecticidal constituent of R. chalepensis leaves was isolated by chromatographic techniques, and identified as quinoline-4-carbaldehyde (C10H7NO). Based on the LD50 values, the most toxic compound against S. oryzae was quinoline (0.063 mg/cm2), followed by quinoline-4-carbaldehyde (0.084 mg/cm2), and quinoline-3-carbaldehyde (0.173 mg/cm2) using the fumigant method. In the contact method, the most active compound against S. oryzae was quinoline (0.057 mg/cm2), followed by quinoline-4-carbaldehyde (0.065 mg/cm2), and quinoline-3-carbaldehyde (0.092 mg/cm2). Changing the position of aldehyde groups in the quinoline skeleton increases the insecticidal activities against S. oryzae. Furthermore, these results suggest that naturally occurring quinoline-4-carbaldehyde and its derivatives could have potential for managing populations of insect pests affecting stored food products.