Antioxidant and Antidiabetic Activities of Aralia elata Seeds

• Published in: Journal of applied biological chemistry 2008, 51(3), , pp.111-116
• Main Authors: Hu, Weicheng (Kangwon National University, Chuncheon, Republic of Korea), Jung, M.J. (Kangwon National University, Chuncheon, Republic of Korea), Heo, S.I. (Kangwon National University, Chuncheon, Republic of Korea), Wang, M.H. (Kangwon National University, Chuncheon, Republic of Korea), E-mail: [e-mail]
• Format: Article
• Language: English
• Subjects: ANTIOXIDANTES; ANTIOXIDANTS; ANTIOXYDANT; Aralia elata seeds; metal chelating-glucosidase; 농학
• ISSN: 1976-0442; 2234-7941
• DOI: 10.3839/jabc.2008.020

Aralia elata seeds were successively extracted with water, methanol, ethanol, acetone and chloroform. The crude extracts were investigated for antioxidant and antidiabetic activities. The antioxidant properties of various extracts were evaluated by antioxidant tests, such as DPPH free radical-scavenging activity, hydroxyl radical-scavenging assay, metal-chelating activity, lipid peroxidation inhibition activity and reducing power assay. The 70% methanol extract exhibited the highest activity in the in vitro models of DPPH free radical-scavenging activity, metal-chelating activity, and reducing power assay. Acetone extract showed good effects on lipid peroxidation inhibition and hydroxyl radical-scavenging assay at a low concentration. In addition, the α-glucosidase inhibition assay showed that 70% methanol extract had the highest activity. These results indicate the high possibility of using A. elata seeds for medical application due to their efficient antioxidant properties.