Practicality and importance of selected endothelial dysfunction measurement techniques: review

The measurement of endothelial dysfunction (ED) has importance in that it indicates the presence of coronary artery disease (Kuvin et al. in J Am Coll Cardiol 38(7):1843–1849, 2001 ) in addition to acting as a predictor of future adverse events (Halcox et al. in Circulation 106:653–658, 2002 ). Vari...

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Bibliographic Details
Published in:Biomedical engineering letters 2019, 9(1), , pp.87-95
Main Authors: Whitt, Michael D., Jackson, Mark J.
Format: Article
Language:English
Subjects:
Biological and Medical Physics
Biomedical Engineering and Bioengineering
Biomedicine
Biophysics
Cardiovascular disease
Cardiovascular diseases
Coronary artery
Coronary artery disease
Engineering
Heart diseases
Measurement techniques
Medical and Radiation Physics
Review
Review Article
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Summary:The measurement of endothelial dysfunction (ED) has importance in that it indicates the presence of coronary artery disease (Kuvin et al. in J Am Coll Cardiol 38(7):1843–1849, 2001 ) in addition to acting as a predictor of future adverse events (Halcox et al. in Circulation 106:653–658, 2002 ). Various tools, methods, and metrics exist that can provide an indicator of endothelial dysfunction. Given the significance of ED, it is of utmost importance to find a measurement technique that is reliable, while defining a metric providing a framework for an overall system that is practical, accurate, and repeatable. Success would provide a tool for the early detection of cardiovascular disease not only moving patients that are currently classified as asymptomatic to symptomatic, but also providing a method to monitor the efficacy of treatments.
ISSN:2093-9868
2093-985X
DOI:10.1007/s13534-018-0089-9