Antibacterial activity of dithiothreitol reduced graphene oxide

A green and simple approach is described for the large scale synthesis of reduced graphene oxide (rGO). The transition of graphene oxide (GO) into graphene was confirmed using various analytical techniques. Raman spectroscopy data indicate the partial removal of oxygen-containing functional groups f...

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Bibliographic Details
Published in:Journal of industrial and engineering chemistry (Seoul, Korea) 2013, 19(4), , pp.1280-1288
Main Authors: Gurunathan, Sangiliyandi, Han, Jae Woong, Dayem, Ahmed Abdal, Eppakayala, Vasuki, Park, Mi-Ryung, Kwon, Deug-Nam, Kim, Jin-Hoi
Format: Article
Language:English
Subjects:
Dithiothreitol
E. coli
Escherichia coli
Graphene oxide
Raman spectroscopy
Reduced graphene oxide
UV–visible spectroscopy
화학공학
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Summary:A green and simple approach is described for the large scale synthesis of reduced graphene oxide (rGO). The transition of graphene oxide (GO) into graphene was confirmed using various analytical techniques. Raman spectroscopy data indicate the partial removal of oxygen-containing functional groups from the surface of GO and formation of graphene. X-ray diffraction (XRD) was used to investigate the crystallinity of graphene nanosheets. The antibacterial activity of GO and rGO was evaluated using cell viability, reactive oxygen species (ROS) production and DNA fragmentation assays. The results suggest that GO and rGO possessed an excellent antimicrobial activity against Escherichia coli.
ISSN:1226-086X
1876-794X
DOI:10.1016/j.jiec.2012.12.029