Suppressing breast cancer by exercise: consideration to animal models and exercise protocols

• Published in: Journal of exercise nutrition & biochemistry 2020, 24(2), , pp.22-29
• Main Authors: Lee, Jea Jun, Beak, Suji, Ahn, Sang Hyun, Moon, Byung Seok, Kim, Jisu, Lee, Kang Pa
• Format: Article
• Language: English
• Subjects: Review; 체육
• ISSN: 2233-6842; 2233-6842; 2733-7545
• DOI: 10.20463/pan.2020.0011

[Purpose] Exercise is thought to have a significant effect on chemotherapy. Previous studies have reported that exercise can increase patient survival. Therefore, in this review, we summarized various animal models to analyze the effects of exercise on breast cancer. [Methods] In this review, we summarized the types of breast cancer animal models from various reports. In addition, we analyzed the effects of exercise on anti-cancer factors in breast cancer animal models. [Results] The purpose of this review was to systematically investigate the issue of suppressing breast cancer using exercise. Their claims included: (a) increase in survival rate through exercise; (b) the intensity of exercise that should be consistent and increased; (c) mechanism for inhibiting carcinogenesis through exercise; (d) The effects of exercise on anti-cancer function. [Conclusion] This review suggested the necessity of various animal models for nonclinical studies before breast cancer clinical trials. It also provides evidence to support the view that exercise plays an important role in prevention or treatment by affecting anti-cancer factors. KCI Citation Count: 0