Formulation of highly purified fenugreek gum based silica lipid drug delivery system for simvastatin with enhanced dissolution rate and in vitro characterization

In current study, highly purified fenugreek gum (HPFG) isolated by patented method explored as emulsifier and hydrophilic solid carrier in drug delivery system. Anti-hyperlipidemic drug simvastatin (SIM) was selected as drug model for the study as it is associated with poorly water solubility and lo...

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Bibliographic Details
Published in:Journal of pharmaceutical investigation 2013, 43(5), , pp.363-373
Main Authors: Sav, Ajay Kumar, Ali, Meer Tarique, Fule, Ritesh Amol, Amin, Purnima Dhanraj
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Research Article
약학
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Summary:In current study, highly purified fenugreek gum (HPFG) isolated by patented method explored as emulsifier and hydrophilic solid carrier in drug delivery system. Anti-hyperlipidemic drug simvastatin (SIM) was selected as drug model for the study as it is associated with poorly water solubility and low bioavailability problems (
ISSN:2093-5552
2093-6214
DOI:10.1007/s40005-013-0081-4