Anti-Biofilm Activity of Cell-Free Supernatant of Saccharomyces cerevisiae against Staphylococcus aureus

Staphylococcus aureus is one of the most common microorganisms and causes foodborne diseases. In particular, biofilm-forming S. aureus is more resistant to antimicrobial agents and sanitizing treatments than planktonic cells. Therefore, this study aimed to investigate the anti-biofilm effects of cel...

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Published in:Journal of microbiology and biotechnology 2020, 30(12), , pp.1854-1861
Main Authors: Kim, Yeon Jin, Yu, Hwan Hee, Park, Yeong Jin, Lee, Na-Kyoung, Paik, Hyun-Dong
Format: Article
Language:English
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Research article
생물학
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Summary:Staphylococcus aureus is one of the most common microorganisms and causes foodborne diseases. In particular, biofilm-forming S. aureus is more resistant to antimicrobial agents and sanitizing treatments than planktonic cells. Therefore, this study aimed to investigate the anti-biofilm effects of cell-free supernatant (CFS) of Saccharomyces cerevisiae isolated from cucumber jangajji compared to grapefruit seed extract (GSE). CFS and GSE inhibited and degraded S. aureus biofilms. The adhesion ability, auto-aggregation, and exopolysaccharide production of CFS-treated S. aureus , compared to those of the control, were significantly decreased. Moreover, biofilm-related gene expression was altered upon CFS treatment. Scanning electron microscopy images confirmed that CFS exerted anti-biofilm effects against S. aureus . Therefore, these results suggest that S. cerevisiae CFS has anti-biofilm potential against S. aureus strains.
ISSN:1017-7825
1738-8872
DOI:10.4014/jmb.2008.08053