Alcohol associated liver cirrhotics have higher mortality after index hospitalization: Long-term data of 5,138 patients

• Published in: Clinical and molecular hepatology 2021, 27(1), , pp.175-185
• Main Authors: Jain, Priyanka, Shasthry, Saggere Muralikrishna, Choudhury, Ashok Kumar, Maiwall, Rakhi, Kumar, Guresh, Bharadwaj, Ankit, Arora, Vinod, Vijayaraghavan, Rajan, Jindal, Ankur, Sharma, Manoj Kumar, Bhatia, Vikram, Sarin, Shiv Kumar
• Format: Article
• Language: English
• Subjects: Age; Alcohol; Ascites; bleeding; cirrhosis; Diabetes; Etiology; Hepatitis B; Hepatitis C; Hospitalization; Hospitals; Kidneys; Liver cancer; Liver cirrhosis; Liver diseases; Liver transplants; Morbidity; Mortality; Original; Patients; Sepsis; Viral infections; 내과학
• ISSN: 2287-2728; 2287-285X
• DOI: 10.3350/cmh.2020.0068

Liver cirrhosis is an important cause of morbidity and mortality globally. Every episode of decompensation and hospitalization reduces survival. We studied the clinical profile and long-term outcomes comparing alcohol-related cirrhosis (ALC) and non-ALC. Cirrhosis patients at index hospitalisation (from January 2010 to June 2017), with ≥1 year follow-up were included. Five thousand and one hundred thirty-eight cirrhosis patients (age, 49.8±14.6 years; male, 79.5%; alcohol, 39.5%; Child-A:B:C, 11.7%:41.6%:46.8%) from their index hospitalization were analysed. The median time from diagnosis of cirrhosis to index hospitalization was 2 years (0.2-10). One thousand and seven hundred seven patients (33.2%) died within a year; 1,248 (24.3%) during index hospitalization. 59.5% (2,316/3,890) of the survivors, required at least one readmission, with additional mortality of 19.8% (459/2,316). ALC compared to non-ALC were more often (P