Primary intracranial leiomyosarcoma presenting with frontal bone mass: a case report

Primary intracranial mesenchymal neoplasms are rare tumors. These tumors are usually metastatic disease from other primary sites. We presented a 31-year-old man with a 6-month history of gradually enlarging frontal mass and positional headache. There was no other symptom demonstrating other organs&#...

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Bibliographic Details
Published in:Radiation oncology journal 2020, 38(4), , pp.282-286
Main Authors: Kamian, Shaghayegh, Ebrahimi, Abdolali, Zadeh, Kaveh Ebrahim, Behzadi, Behnaz
Format: Article
Language:English
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Case Report
방사선과학
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Summary:Primary intracranial mesenchymal neoplasms are rare tumors. These tumors are usually metastatic disease from other primary sites. We presented a 31-year-old man with a 6-month history of gradually enlarging frontal mass and positional headache. There was no other symptom demonstrating other organs' involvement. The patient underwent an uncomplicated craniotomy with clear surgical margins. The pathology review and the immunohistochemistry staining confirmed leiomyosarcoma grade II. We prescribed radiation therapy with tumor dose of 60 Gy in 30 fractions with conformal treatment planning to the tumor bed. As this disease has a high potency for metastasis, we advised four courses of single agent doxorubicin chemotherapy 75 mg/m2 every 4 weeks starting one month after the end of radiotherapy. In the last follow-up visit 34 months later, the patient was disease free in physical exam and imaging findings.
ISSN:2234-1900
2234-3156
2234-3164
DOI:10.3857/roj.2020.00577