Different Seasonal Variations of Potassium in Hemodialysis Patients with High Longitudinal Potassium Levels: A Multicenter Cohort Study Using DialysisNet

• Published in: Yonsei medical journal 2021, 62(4), , pp.315-324
• Main Authors: Kim, Yunmi, Yun, Seong Han, Koo, Hoseok, Hwang, Subin, Kim, Hyo Jin, Lee, Sunhwa, Baek, Hyunjeong, Kim, Hye Hyeon, Lee, Kye Hwa, Kim, Ju Han, Park, Ji In, Yoo, Kyung Don
• Format: Article
• Language: English
• Subjects: Cohort Studies; Humans; Original; Potassium; Renal Dialysis; Seasons; 의학일반
• ISSN: 0513-5796; 1976-2437
• DOI: 10.3349/ymj.2021.62.4.315

To determine seasonal variations in serum potassium levels among hemodialysis patients. This was a multicenter cohort study of patients whounderwent hemodialysis and were registered in DialysisNet at our four associated general hospitals between January and December 2016. Month-to-month potassium variability was quantified as SD/√{n/(n-1)}, and a non-hierarchical method was used to cluster groups according to potassium trajectories. Seasonal variations in potassium levels were analyzed using a cosinor analysis. The analysis was performed on 279 patients with a mean potassium level of 5.08±0.58 mmol/L. After clustering, 52.3% (n=146) of patients were included in the moderate group (K , 4.6±0.4 mmol/L) and 47.7% (n=133) in the high group (K , 5.6±0.4 mmol/L). The mean potassium level peaked in January in the moderate group (4.83±0.74 mmol/L) and in August in the high group (5.51±0.70 mmol/L). In the high potassium group, potassium levels were significantly higher in summer than in autumn (