Clinical behaviour and outcome in pediatric glioblastoma: current scenario

Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from def...

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Published in:Radiation oncology journal 2021, 39(1), , pp.72-77
Main Authors: Singla, Aditya Kumar, Madan, Renu, Gupta, Kirti, Goyal, Shikha, Kumar, Narendra, Sahoo, Sushant Kumar, Uppal, Deepak K, Ahuja, Chirag K
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Case Report
방사선과학
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creator Singla, Aditya Kumar
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description Pediatric glioblastoma (pGBM) is a rare entity accounting for only approximately 3% of all childhood brain tumors. Treatment guidelines for pGBM have been extrapolated from those in adult glioblastoma. Rarity of pGBM and underrepresentation of pediatric population in major studies precludes from defining the ideal treatment protocol for these patients. Maximum safe resection is performed in most of the cases followed by postoperative radiotherapy in children over 3 years of age. Benefit of temozolomide is unclear in these patients. Here, we present the clinicopathological details and outcome of six pGBM patients treated at our institute in 2018-2019.
doi_str_mv 10.3857/roj.2020.00591
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subjects Case Report
방사선과학
title Clinical behaviour and outcome in pediatric glioblastoma: current scenario
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