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Trans-acting regulators of ribonuclease activity
RNA metabolism needs to be tightly regulated in response to changes in cellular physiology. Ribonucleases (RNases) play an essential role in almost all aspects of RNA metabolism, including processing, degradation, and recycling of RNA molecules. Thus, living systems have evolved to regulate RNase ac...
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Published in: | The journal of microbiology 2021, 59(4), , pp.341-359 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | RNA metabolism needs to be tightly regulated in response to changes in cellular physiology. Ribonucleases (RNases) play an essential role in almost all aspects of RNA metabolism, including processing, degradation, and recycling of RNA molecules. Thus, living systems have evolved to regulate RNase activity at multiple levels, including transcription, post-transcription, post-translation, and cellular localization. In addition, various
trans
-acting regulators of RNase activity have been discovered in recent years. This review focuses on the physiological roles and underlying mechanisms of
trans
-acting regulators of RNase activity. |
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ISSN: | 1225-8873 1976-3794 1976-3794 |
DOI: | 10.1007/s12275-021-0650-6 |