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Trans-acting regulators of ribonuclease activity

RNA metabolism needs to be tightly regulated in response to changes in cellular physiology. Ribonucleases (RNases) play an essential role in almost all aspects of RNA metabolism, including processing, degradation, and recycling of RNA molecules. Thus, living systems have evolved to regulate RNase ac...

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Bibliographic Details
Published in:The journal of microbiology 2021, 59(4), , pp.341-359
Main Authors: Lee, Jaejin, Lee, Minho, Lee, Kangseok
Format: Article
Language:English
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Summary:RNA metabolism needs to be tightly regulated in response to changes in cellular physiology. Ribonucleases (RNases) play an essential role in almost all aspects of RNA metabolism, including processing, degradation, and recycling of RNA molecules. Thus, living systems have evolved to regulate RNase activity at multiple levels, including transcription, post-transcription, post-translation, and cellular localization. In addition, various trans -acting regulators of RNase activity have been discovered in recent years. This review focuses on the physiological roles and underlying mechanisms of trans -acting regulators of RNase activity.
ISSN:1225-8873
1976-3794
1976-3794
DOI:10.1007/s12275-021-0650-6