Factors Contributing to an Efficacious Endovascular Treatment for Acute Ischemic Stroke in Asian Population

Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby r...

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Bibliographic Details
Published in:Neurointervention 2021, 16(2), , pp.91-110
Main Authors: Lee, Jin Soo, Hwang, Yang-Ha, Sohn, Sung-Il
Format: Article
Language:English
Subjects:
acute kidney injury
cerebral infarction
diabetes mellitus
endovascular procedures
intracranial atherosclerosis
reperfusion injury
Review
방사선과학
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Summary:Although randomized control trials about endovascular treatment (EVT) of emergent large vessel occlusion (LVO) have demonstrated the success of mechanical thrombectomy as the choice of treatment, a wide range of caveats remain unaddressed. Asian patients were rarely included in the trials, thereby raising the question of whether the treatment could be generalized. In addition, there remains a concern on the feasibility of the method with respect to its application against intracranial atherosclerosis (ICAS)-related LVO, frequently observed in the Asian population. It is important to include evidence on ICAS LVO from Asian countries in the future for a comprehensive understanding of LVO etiology. Besides the issues with EVT, prognostic concerns in diabetes patients, acute kidney injury following EVT, neuroprotective management against reperfusion injury, and other peri-EVT issues should be considered in clinical practice. In the current article, we present an in-depth review of the literature that revises information pertaining to such concerns.
ISSN:2093-9043
2233-6273
DOI:10.5469/neuroint.2020.00339