Longitudinal Change in Myocardial Function and Clinical Parameters in Middle-Aged Subjects: A 3-Year Follow-up Study

Metabolic syndrome (MetS) is closely associated with the aging process. However, changes in metabolic conditions and cardiac function that occur in middle aged population remain unclear. We evaluated longitudinal changes in metabolic parameters and cardiac function during a 3-year period in subjects...

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Bibliographic Details
Published in:Diabetes & metabolism journal 2021, 45(5), 187, pp.719-729
Main Authors: Cho, Dong-Hyuk, Joo, Hyung Joon, Kim, Mi-Na, Kim, Hee-Dong, Lim, Do-Sun, Park, Seong-Mi
Format: Article
Language:English
Subjects:
Adiposity
Female
Follow-Up Studies
Humans
longitudinal studies
Male
metabolic syndrome
Metabolic Syndrome - epidemiology
Middle Aged
Myocardium
Original
sex characteristics
ventricular dysfunction
Waist Circumference
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Summary:Metabolic syndrome (MetS) is closely associated with the aging process. However, changes in metabolic conditions and cardiac function that occur in middle aged population remain unclear. We evaluated longitudinal changes in metabolic parameters and cardiac function during a 3-year period in subjects with suspected MetS. We studied 191 participants with suspected MetS at baseline and after 3 years. Anthropometric parameters, including waist circumference (WC), and metabolic parameters, including fasting blood glucose and lipid profile were measured. Conventional echocardiography with two-dimensional speckle tracking was performed. Mean age was 56.2±4.4 years, and there were 97 women (50.8%). Men had increased WC and triglycerides (TG) (WC 91.2±6.8 cm vs. 84.0±8.0 cm, P
ISSN:2233-6079
2233-6087
2233-6087
DOI:10.4093/dmj.2020.0132