Increased depression risk in patients with abdominal aortic aneurysm: a nationwide cohort study

• Published in: Annals of surgical treatment and research 2021, 101(5), , pp.291-298
• Main Authors: Kim, Mi-Hyeong, Yoo, Ju-Hwan, Cho, Hyung-Jin, Ko, Kyung-Jai, Jun, Kang-Woong, Han, Kyung-do, Hwang, Jeong-Kye
• Format: Article
• Language: English
• Subjects: Original; 일반외과학
• ISSN: 2288-6575; 2288-6796
• DOI: 10.4174/astr.2021.101.5.291

Abdominal aortic aneurysm (AAA) is a critical disease. Most studies of AAA consider reoperation rate, complications, or mortality, but do not consider a patient's mental state. However, there is a possibility of interaction between AAA and depression in disease development and prognosis. We investigated the incidence and risk ratio of depression in patients with AAA using nationwide data. We selected subjects from National Health Insurance System database who were diagnosed with AAA between 2009 and 2015 and survived at least 1 year after diagnosis or AAA surgery (n = 10,373). We determined the control group using propensity score matching by age and sex. The control group had about 3 times the number of subjects as the AAA cohort (n = 31,119). The incidence of depression was 1.4 times higher in the AAA group than the control group. We further analyzed the incidence of depression in the AAA group according to treatment modalities (nonsurgical surgical or nonsurgical open surgical aneurysm repair endovascular aneurysm repair) but found no significant difference among them. The incidence of depression was significantly higher in patients aged