Metformin use and cardiovascular outcomes in patients with diabetes and chronic kidney disease: a nationwide cohort study

Metformin has recently been shown not to increase the risk of lactic acidosis in patients with chronic kidney disease (CKD). Thus, the criteria for metformin use in this population has expanded. However, the relationship between metformin use and clinical outcomes in CKD remains controversial. This...

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Bibliographic Details
Published in:Kidney research and clinical practice 2021, 40(4), , pp.660-672
Main Authors: Kim, Min-Ho, Oh, Hyung Jung, Kwon, Soon Hyo, Jeon, Jin Seok, Noh, Hyunjin, Han, Dong Cheol, Kim, Hyoungnae, Ryu, Dong-Ryeol
Format: Article
Language:English
Subjects:
chronic kidney disease
metformin
mortality
Original
renal insufficiency
내과학
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Summary:Metformin has recently been shown not to increase the risk of lactic acidosis in patients with chronic kidney disease (CKD). Thus, the criteria for metformin use in this population has expanded. However, the relationship between metformin use and clinical outcomes in CKD remains controversial. This study considered data from 97,713 diabetes patients with an estimated glomerular filtration rate of
ISSN:2211-9132
2211-9140
DOI:10.23876/j.krcp.20.222