Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells

Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shin...

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Published in:Food science and biotechnology 2022, 31(5), , pp.617-625
Main Authors: Choi, Su-Young, Lee, Su Yeon, Kim, Hyung Gyun, Jeong, Jae Cheon, Batara, Don Carlo, Kim, Sung-Hak, Cho, Jeong-Yong
Format: Article
Language:English
Subjects:
Adipocytes
Adipogenesis
Adiponectin
Amino acids
Antioxidants
Bioactive compounds
CCAAT/enhancer-binding protein
Chemistry
Chemistry and Materials Science
Cytotoxicity
Food Science
Gene expression
Leptin
Lipids
Magnetic resonance spectroscopy
Mycosporine-like amino acids
NMR
NMR spectroscopy
Nuclear magnetic resonance
Nutrition
Porphyra
Preadipocytes
Research Article
Shinorine
식품과학
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Summary:Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver ( Porphyra dentata ) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (
ISSN:1226-7708
2092-6456
DOI:10.1007/s10068-022-01055-6