Continuous nanoparticle production by microfluidic-based emulsion, mixing and crystallization

• Published in: Journal of solid state chemistry 2007-09, Vol.180 (9), p.2625-2629
• Main Authors: Su, Y.-F., Kim, H., Kovenklioglu, S., Lee, W.Y.
• Format: Article
• Language: English
• Subjects: AMINES; AMMONIUM SULFATES; BARIUM CHLORIDES; BARIUM SULFATES; Chemical synthesis methods; Condensed matter: structure, mechanical and thermal properties; Cross-disciplinary physics: materials science; rheology; CRYSTALLIZATION; Emulsion; Equations of state, phase equilibria, and phase transitions; Exact sciences and technology; INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; Low-dimensional structures (superlattices, quantum well structures, multilayers): structure, and nonelectronic properties; Materials science; Methods of nanofabrication; Microfluidics; Microreactor; Nanoparticles; Nanoscale materials and structures: fabrication and characterization; NANOSTRUCTURES; Other topics in nanoscale materials and structures; Physics; PYRIDINES; RECRYSTALLIZATION; Solid-solid transitions; Specific phase transitions; Surfaces and interfaces; thin films and whiskers (structure and nonelectronic properties)
• ISSN: 0022-4596; 1095-726X
• DOI: 10.1016/j.jssc.2007.06.033

BaSO 4 and 2,2′-dipyridylamine (DPA) nanoparticles were synthesized as reactive crystallization and anti-solvent recrystallization examples, respectively, of using the microfluidic-based emulsion and mixing approach as a new avenue of continuously producing inorganic and organic nanoparticles. BaSO 4 nanoparticles in the size range of 15–100 nm were reactively precipitated within the confinement of an aqueous droplet which was coalesced from two separate aqueous droplets containing BaCl 2 and (NH 4) 2SO 4 using a three T-junction micromixer configuration constructed with commercially available simple tubing and fitting supplies. Also, DPA nanoparticles of about 200 nm were crystallized by combining DPA+ethanol and water droplets using the same micromixer configuration. BaSO 4 and 2,2′-dipyridylamine (DPA) nanoparticles were synthesized as reactive crystallization and anti-solvent recrystallization examples, respectively, of using the microfluidic-based emulsion and mixing approach as a new avenue of continuously producing inorganic and organic nanoparticles.