Cerebral lipiodol embolism: a complication of transcatheter arterial chemoembolization for hepatocellular carcinoma

We report a case of cerebral lipiodol embolism following transcatheter chemoembolization (TACE) for hepatocellular carcinoma. A 70-year-old woman with a large unresectable hepatocellular carcinoma underwent TACE. Her level of consciousness deteriorated after the procedure, and magnetic resonance ima...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2007-06, Vol.30 (3), p.512-514
Main Authors: Matsumoto, Koichi, Nojiri, Junichi, Takase, Yukinori, Egashira, Yoshikazu, Azama, Shinichi, Kato, Akira, Kitahara, Kenji, Miyazaki, Koji, Kudo, Sho
Format: Article
Language:English
Subjects:
Aged
Brain - drug effects
Brain - pathology
BYPASSES
Carcinoma, Hepatocellular - therapy
Chemoembolization, Therapeutic - adverse effects
COMPUTERIZED TOMOGRAPHY
Contrast Media - administration & dosage
Contrast Media - adverse effects
Diagnostic Imaging
Epirubicin - administration & dosage
Fatal Outcome
Female
HEPATOMAS
Humans
Intracranial Embolism - chemically induced
Intracranial Embolism - diagnosis
Iodized Oil - adverse effects
LIPIODOL
Liver cirrhosis
Liver Neoplasms - therapy
Medical research
Neoplasm Recurrence, Local - therapy
NMR IMAGING
RADIOLOGY AND NUCLEAR MEDICINE
SURGERY
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Summary:We report a case of cerebral lipiodol embolism following transcatheter chemoembolization (TACE) for hepatocellular carcinoma. A 70-year-old woman with a large unresectable hepatocellular carcinoma underwent TACE. Her level of consciousness deteriorated after the procedure, and magnetic resonance imaging and non-contrast computed tomography revealed a cerebral lipiodol embolism. Despite intensive care, the patient died 2 weeks later. The complication might have been due to systemic-pulmonary shunts caused by previous surgeries and/or direct invasion of the recurrent tumor.
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-006-0092-x