Freehand two-step CT-guided brain tumor biopsy: a fast and effective interventional procedure in selected patients

To evaluate the efficacy and safety of CT-guided needle biopsy of brain lesions without a stereotactic device, and to determine the best possible indications for this technique. From February 2001 to February 2004, 20 patients (12 men, 8 women; age 61-82 years) underwent CT-guided brain lesion biops...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2006-04, Vol.29 (2), p.264-269
Main Authors: Thanos, Loukas, Mylona, Sofia, Galani, Panagiota, Kalioras, Vasilios, Pomoni, Maria, Batakis, Nikolaos
Format: Article
Language:English
Subjects:
Aged
BIOMEDICAL RADIOGRAPHY
BIOPSY
Biopsy, Needle
BRAIN
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - pathology
COMPUTERIZED TOMOGRAPHY
COST
DEATH
DIAGNOSIS
Female
HEMATOMAS
Humans
IMAGE PROCESSING
INFLAMMATION
Male
Medical treatment
Middle Aged
NEOPLASMS
PATIENTS
Radiography, Interventional
RADIOLOGY AND NUCLEAR MEDICINE
Tomography, X-Ray Computed
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Summary:To evaluate the efficacy and safety of CT-guided needle biopsy of brain lesions without a stereotactic device, and to determine the best possible indications for this technique. From February 2001 to February 2004, 20 patients (12 men, 8 women; age 61-82 years) underwent CT-guided brain lesion biopsy. The procedure started with a brain CT scan for lesion localization and for selection of the inlet for needle insertion. The patient was then transported to the operating room where cranioanatrisis was performed. Subsequently, the biopsy was performed under CT guidance using a 14G brain biopsy needle with a blind smooth end and lateral holes. At the end of the biopsy, the field was checked for possible complications with a CT scan. Histopathologic results were: brain tumor in 16 patients (80%), inflammatory process in 3 (15%), and no conclusive diagnosis in 1 (5%). A repeat of the process was required in 2 patients. A minor complication of local hematoma was found in 1 patient (5%). There were no deaths or other serious complications. CT-guided biopsy is a reliable method for histopathologic diagnosis of brain lesions in selected cases. It is a simple, fast, effective, low-cost procedure with minimal complications, indicated especially for superficial and large tumors.
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-005-0015-2