Implementation of a Lateral TBI protocol in a Mexican Cancer Center

The development of a Lateral Total Body Irradiation protocol to be implemented at a High Specialty Medical Unit in Mexico as preparatory regimen for bone marrow transplant and treatment of several lymphomas is presented. This protocol was developed following AAPM specifications and has been validate...

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Bibliographic Details
Main Authors: Mesa, Francisco, Esquivel, Carlos, Eng, Tony, Papanikolaou, Niko, Sosa, Modesto A
Format: Conference Proceeding
Language:English
Subjects:
BIOLOGICAL RADIATION EFFECTS
BONE MARROW
DOSES
IN VIVO
LUNGS
LYMPHOMAS
MEXICO
PATIENTS
PHOTON BEAMS
RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
THERMOLUMINESCENT DOSIMETRY
TRANSPLANTS
WHOLE-BODY IRRADIATION
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Summary:The development of a Lateral Total Body Irradiation protocol to be implemented at a High Specialty Medical Unit in Mexico as preparatory regimen for bone marrow transplant and treatment of several lymphomas is presented. This protocol was developed following AAPM specifications and has been validated for application at a cancer care center in United States. This protocol fundamentally focuses on patient care, avoiding instability and discomfort that may be encountered by other treatment regimes. In vivo dose verification with TLD-100 chips for each anatomical region of interest was utilized. TLD-100 chips were calibrated using a 6 MV photon beam for 10-120 cGy. Experimental results show TLD measurements with an error less than 1%. Standard deviations for calculated and measured doses for seven patients have been obtained. Data gathered for different levels of compensation indicate that a 3% measured tolerance level is acceptable. TLD point-dose measurements have been used to verify the dose beyond partial transmission lung blocks. Dose measurements beyond the lung block showed variation about 50% respects to prescribe dose. Midplane doses to the other anatomical sites were less than 2.5 % respect of the prescribed dose.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.2979311