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Opto-acoustic diagnostics of the thermal action of high-intensity focused ultrasound on biological tissues: the possibility of its applications and model experiments

The possibility of using the opto-acoustic (OA) method for monitoring high-intensity ultrasonic therapy is studied. The optical properties of raw and boiled liver samples used as the undamaged model tissue and tissue destroyed by ultrasound, respectively, are measured. Experiments are performed with...

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Published in:Quantum electronics (Woodbury, N.Y.) N.Y.), 2006-12, Vol.36 (12), p.1097-1102
Main Authors: Khokhlova, Tanya D, Pelivanov, Ivan M, Sapozhnikov, Oleg A, Solomatin, Vladimir S, Karabutov, Aleksander A
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container_issue 12
container_start_page 1097
container_title Quantum electronics (Woodbury, N.Y.)
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creator Khokhlova, Tanya D
Pelivanov, Ivan M
Sapozhnikov, Oleg A
Solomatin, Vladimir S
Karabutov, Aleksander A
description The possibility of using the opto-acoustic (OA) method for monitoring high-intensity ultrasonic therapy is studied. The optical properties of raw and boiled liver samples used as the undamaged model tissue and tissue destroyed by ultrasound, respectively, are measured. Experiments are performed with samples consisting of several alternating layers of raw and boiled liver of different thickness. The position and transverse size of the thermal lesion were determined from the temporal shape of the OA signals. The results of measurements are compared with the real size and position of the thermal lesion determined from the subsequent cuts of the sample. It is shown that the OA method permits the diagnostics of variations in biological tissues upon ultrasonic therapy. (special issue devoted to multiple radiation scattering in random media)
doi_str_mv 10.1070/QE2006v036n12ABEH013262
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subjects ACOUSTIC MONITORING
ACOUSTIC TESTING
BODY
DIGESTIVE SYSTEM
DIMENSIONS
GLANDS
LAYERS
LIVER
MATERIALS TESTING
MEDICINE
MONITORING
NONDESTRUCTIVE TESTING
OPTICAL EQUIPMENT
OPTICAL PROPERTIES
ORGANS
PHYSICAL PROPERTIES
RADIOLOGY AND NUCLEAR MEDICINE
SCATTERING
SIGNALS
SOUND WAVES
TESTING
THERAPY
THICKNESS
ULTRASONIC WAVES
title Opto-acoustic diagnostics of the thermal action of high-intensity focused ultrasound on biological tissues: the possibility of its applications and model experiments
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