Single shot cell irradiations with laser-driven protons

Ion beams are relevant for radiobiological studies in basic research and for application in tumor therapy. Here we present a method to generate nanosecond proton bunches with single shot doses of up to 7 Gray by a tabletop high-power laser. Although in their infancy, laser-ion accelerators allow stu...

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Bibliographic Details
Published in:AIP conference proceedings 2013-07, Vol.1546 (1)
Main Authors: Humble, N., Schmid, T. E., Zlobinskaya, O., Wilkens, J. J., Allinger, K., Hilz, P., Ma, W., Reinhardt, S., Bin, J., Kiefer, D., Schreiber, J., Drexler, G. A., Friedl, A.
Format: Article
Language:English
Subjects:
ACCELERATORS
BEAM BUNCHING
BEAM PRODUCTION
BIOLOGICAL RADIATION EFFECTS
HUMAN POPULATIONS
ION BEAMS
LASER-PRODUCED PLASMA
LASERS
NEOPLASMS
PARTICLE ACCELERATORS
PROTON BEAMS
PROTONS
RADIATION DOSE UNITS
RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
RBE
TUMOR CELLS
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Summary:Ion beams are relevant for radiobiological studies in basic research and for application in tumor therapy. Here we present a method to generate nanosecond proton bunches with single shot doses of up to 7 Gray by a tabletop high-power laser. Although in their infancy, laser-ion accelerators allow studying fast radiobiological processes at small-scale laboratories as exemplarily demonstrated by measurements of the relative biological effectiveness of protons in human tumor cells.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.4816611