Evaluation of Liver Stiffness After Radioembolization by Real-Time ShearWave™ Elastography: Preliminary Study

Purpose To evaluate the effect of ShearWave™ elastography (SWE) for the assessment of liver fibrosis after radioembolization (RE) in patients with liver malignancies. Materials and Methods We prospectively examined the effects of SWE before and after RE in 17 adult patients, from June 2012 to Septem...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2015-08, Vol.38 (4), p.957-963
Main Authors: Bas, Ahmet, Samanci, Cesur, Gulsen, Fatih, Cantasdemir, Murat, Kabasakal, Levent, Kantarci, Fatih, Numan, Furuzan
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
ANIMAL TISSUES
BIOMEDICAL RADIOGRAPHY
Brachytherapy
Carcinoma, Hepatocellular - complications
Carcinoma, Hepatocellular - diagnostic imaging
Carcinoma, Hepatocellular - radiotherapy
Cardiology
Clinical Investigation
Elasticity Imaging Techniques - methods
EVALUATION
Female
FIBROSIS
FLEXIBILITY
Follow-Up Studies
HEPATITIS
Hepatitis B - complications
Hepatitis C - complications
HEPATOMAS
Humans
Image Interpretation, Computer-Assisted
Imaging
LIVER
Liver - diagnostic imaging
Liver - radiation effects
Liver Cirrhosis - diagnostic imaging
Liver Neoplasms - complications
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - radiotherapy
Male
MATERIALS
Medicine
Medicine & Public Health
Middle Aged
Nuclear Medicine
PATIENTS
PLANT TISSUES
POPULATIONS
Prospective Studies
RADIOEMBOLIZATION
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
Ultrasound
VASCULAR DISEASES
VIRUSES
Yttrium Radioisotopes - therapeutic use
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Summary:Purpose To evaluate the effect of ShearWave™ elastography (SWE) for the assessment of liver fibrosis after radioembolization (RE) in patients with liver malignancies. Materials and Methods We prospectively examined the effects of SWE before and after RE in 17 adult patients, from June 2012 to September 2013. All patients underwent SWE within 1 month before and 3 months (96.3 ± 22.9 days) after RE. Measurements were taken in segments III, IV, V, and VI (lateral/medial left lobe and anterior/posterior right lobe, respectively). Liver stiffness was studied in the 39 treated segments. Results The mean stiffness of liver tissue according to the pre-RE SWE measurements was not different from the post-RE SWE measurements in the segments that did not undergo RE. Conversely, segments treated with RE were significantly stiffer according to the post-RE SWE measurements (mean SWE 17.4 kPa) than according to the baseline measurements (7.0 kPa) ( p  
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-014-1021-z