Properties of radiation-synthesized polyvinylpyrrolidone/chitosan hydrogel blends

Poly(vinylpyrrolidone) (PVP)-crosslinked chitosan hydrogels were prepared by gamma radiation at various doses; 1, 3 5, 7, 10, 15, 20, 25 and 30kGy. Gamma radiation was used as a crosslinking tool which requires no chemical initiator, no heating process and need no purification step on the end produc...

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Bibliographic Details
Main Authors: Mahmud, Maznah, Radiation Processing Technology Division, Malaysian Nuclear Agency, 43000 Kajang, Selangor, Daik, Rusli, Adam, Zainah
Format: Conference Proceeding
Language:English
Subjects:
AMINO ACIDS
Chitosan
CROSS-LINKING
Crosslinking
Formulations
GAMMA RADIATION
Gamma rays
HYDROGELS
INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY
IRRADIATION
LACTIC ACID
Molecular weight
OLIGOSACCHARIDES
Organic chemistry
PH VALUE
PHYSICAL PROPERTIES
Polymer blends
Polyvinylpyrrolidone
PURIFICATION
PVP
Radiation dosage
RADIATION DOSES
RADIATION EFFECTS
SCANNING ELECTRON MICROSCOPY
SWELLING
Syneresis
Synthesis
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Summary:Poly(vinylpyrrolidone) (PVP)-crosslinked chitosan hydrogels were prepared by gamma radiation at various doses; 1, 3 5, 7, 10, 15, 20, 25 and 30kGy. Gamma radiation was used as a crosslinking tool which requires no chemical initiator, no heating process and need no purification step on the end products obtained. The hydrogel formulations were composed of 6% chitosan with average molecular weight (Mw) = 48 800 g/mol and 14% PVP with Mw = 10 000 g/mol in 2% lactic acid. Physical properties of hydrogels such as gel fraction and swelling property at pH 5.5 and pH 7.0 as well as syneresis activity were determined. It was found that different radiation dose induces different effect on hydrogels’ network formed. Morphological study of hydrogels has been carried out by scanning electron microscope (SEM). From these preliminary evaluations, it can be concluded that gamma radiation is an effective tool for network development of hydrogels and it also induces enhancement on characteristics of hydrogels synthesized.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.4931310