MRI-guided Wire Localization Surgical Biopsy in an Adolescent Patient with a Difficult to Diagnose Case of Lymphoma

A 17-year-old previously healthy female presented with a progressive soft tissue infiltrative process involving the neck and thorax. Extensive diagnostic evaluation including multiple imaging, laboratory, and biopsy studies was nondiagnostic. Due to an urgent need to establish a diagnosis and severa...

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Bibliographic Details
Published in:Cardiovascular and interventional radiology 2017-01, Vol.40 (1), p.135-138
Main Authors: Thompson, Scott M., Gorny, Krzysztof R., Jondal, Danielle E., Rech, Karen L., Mardini, Samir, Woodrum, David A.
Format: Article
Language:English
Subjects:
Adolescent
ADOLESCENTS
ANESTHESIA
ANIMAL TISSUES
BIOMEDICAL RADIOGRAPHY
BIOPSY
Biopsy, Needle - methods
Cardiology
Case Report
CHEST
DIAGNOSIS
Diagnosis, Differential
EVALUATION
Female
Head and Neck Neoplasms - diagnostic imaging
Head and Neck Neoplasms - pathology
Humans
Image-Guided Biopsy - methods
Imaging
Lymphoma, B-Cell - diagnostic imaging
Lymphoma, B-Cell - pathology
LYMPHOMAS
Magnetic Resonance Imaging, Interventional - methods
Medicine
Medicine & Public Health
MUSCLES
NECK
Neck - diagnostic imaging
Neck - pathology
NMR IMAGING
Nuclear Medicine
PATHOLOGY
PATIENTS
PLANT TISSUES
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
SURGERY
Ultrasound
WIRES
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Description
Summary:A 17-year-old previously healthy female presented with a progressive soft tissue infiltrative process involving the neck and thorax. Extensive diagnostic evaluation including multiple imaging, laboratory, and biopsy studies was nondiagnostic. Due to an urgent need to establish a diagnosis and several previous nondiagnostic biopsies, she was referred to interventional radiology for MRI-guided wire localization immediately prior to open surgical biopsy. Under general anesthesia, wires were placed in the areas of increased T2 signal within the bilateral splenius capitis muscles using intermittent MRI-guidance followed by immediate surgical biopsy down to the wires. Pathology confirmed the diagnosis of diffuse large B-cell lymphoma.
ISSN:0174-1551
1432-086X
DOI:10.1007/s00270-016-1464-5