Photodynamic effect of radiation with the wavelength 405 nm on the cells of microorganisms sensitised by metalloporphyrin compounds

We have studied the photodynamic activity of photosensitisers based on metalloporphyrins. New metalloporphyrin compounds are synthesised and characterised, the quantum yields of the singlet oxygen formation are analysed. It is shown that when the photodynamic effect is implemented using the metallop...

Full description

Saved in:
Bibliographic Details
Published in:Quantum electronics (Woodbury, N.Y.) N.Y.), 2016-01, Vol.46 (6), p.521-527
Main Authors: Korchenova, M V, Tuchina, E S, Shvayko, V Y, Gulkhandanyan, A G, Zakoyan, A A, Kazaryan, R K, Gulkhandanyan, G V, Dzhagarov, B M, Tuchin, V V
Format: Article
Language:English
Subjects:
ANTIBIOTICS
Bacteria
BIOLOGICAL RADIATION EFFECTS
BUTYL RADICALS
ESCHERICHIA COLI
INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY
Microorganisms
OXYGEN
PHOTOSENSITIVITY
PORPHYRINS
PYRIDINE
Quantum electronics
Radicals
STAPHYLOCOCCUS
SYNTHESIS
WAVELENGTHS
ZINC IONS
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We have studied the photodynamic activity of photosensitisers based on metalloporphyrins. New metalloporphyrin compounds are synthesised and characterised, the quantum yields of the singlet oxygen formation are analysed. It is shown that when the photodynamic effect is implemented using the metalloporphyrins with Zn ions and butyl radical in the 3rd and 4th positions of the pyridine ring, the number of opportunistic bacteria, such as Staphylococcus aureus(antibiotic-sensitives and antibiotic-resistant strains), Staphylococcus simulans and Escherichia coli is efficiently reduced by 90% - 99%.
ISSN:1063-7818
1468-4799
DOI:10.1070/QEL16110