Differentiation of hepatic abscess from metastasis on contrast-enhanced dynamic computed tomography in patients with a history of extrahepatic malignancy: emphasis on dynamic change of arterial rim enhancement

Objectives The objective of the study is to identify computed tomography (CT) findings that differentiate hepatic abscess from hepatic metastasis in a patient with a history of extrahepatic malignancy. Materials and methods This retrospective study included 30 patients with 93 hepatic abscesses and...

Full description

Saved in:
Bibliographic Details
Published in:Abdominal imaging 2019-02, Vol.44 (2), p.529-538
Main Authors: Oh, Jae Gu, Choi, Seo-Youn, Lee, Min Hee, Lee, Ji Eun, Yi, Boem Ha, Kim, Seung Soo, Min, Ji Hye, Lee, Bora
Format: Article
Language:English
Subjects:
ABSCESSES
Aged
Aged, 80 and over
Bile ducts
BILIARY TRACT
Computation
Computed tomography
COMPUTERIZED TOMOGRAPHY
Contrast Media
DIAGNOSIS
Diagnosis, Differential
Female
Gastroenterology
Hepatology
Humans
Hyperemia
Imaging
Lesions
LIVER
Liver - diagnostic imaging
Liver Abscess - diagnostic imaging
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - secondary
Male
Malignancy
Medicine
Medicine & Public Health
METASTASES
Metastasis
Middle Aged
MULTIVARIATE ANALYSIS
NEOPLASMS
Neoplasms, Second Primary - diagnostic imaging
NOMOGRAMS
PATIENTS
Radiographic Image Enhancement - methods
Radiology
RADIOLOGY AND NUCLEAR MEDICINE
Retrospective Studies
Sensitivity and Specificity
Tomography, X-Ray Computed - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives The objective of the study is to identify computed tomography (CT) findings that differentiate hepatic abscess from hepatic metastasis in a patient with a history of extrahepatic malignancy. Materials and methods This retrospective study included 30 patients with 93 hepatic abscesses and 40 patients with 125 hepatic metastases who had a history of extrahepatic malignancy and underwent contrast-enhanced dynamic CT with arterial phase (AP) and portal venous phase (PVP). The diagnosis of hepatic abscess and hepatic metastasis was made using pathological confirmation or clinical diagnosis. Margin, patchy parenchymal enhancement, arterial rim enhancement, dynamic change of arterial rim enhancement, size discrepancy of lesions between arterial and portal phases, bile duct dilatation, perilesional hyperemia, and perilesional low density were evaluated by two radiologists independently. Significant findings for differentiating two groups were identified at univariate and multivariate analysis with nomogram for predicting hepatic abscess. Interobserver agreement was also analyzed for each variable. Results Multivariate analysis revealed that patchy parenchymal enhancement ( P 
ISSN:2366-004X
2366-0058
2366-0058
DOI:10.1007/s00261-018-1766-y