Quantification of PET Myocardial Blood Flow

Purpose of Review The aim of this review is to provide an update on quantification of myocardial blood flow (MBF) with positron emission tomography (PET) imaging. Technical and clinical aspects of flow quantification with PET are reviewed. Recent Findings The diagnostic and prognostic values of myoc...

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Bibliographic Details
Published in:Current cardiology reports 2019-03, Vol.21 (3), p.11-11, Article 11
Main Authors: Pelletier-Galarneau, Matthieu, Martineau, Patrick, El Fakhri, Georges
Format: Article
Language:English
Subjects:
BLOOD FLOW
Cardiology
CORONARIES
Coronary Angiography
Coronary Artery Disease - diagnostic imaging
Coronary Circulation
CYCLOTRONS
DISEASES
Fractional Flow Reserve, Myocardial
Humans
Medicine
Medicine & Public Health
Microcirculation
Microvessels - diagnostic imaging
Myocardial Perfusion Imaging - methods
Nuclear Cardiology (V Dilsizian
POSITRON COMPUTED TOMOGRAPHY
Positron-Emission Tomography - methods
RADIOLOGY AND NUCLEAR MEDICINE
Section Editor
Topical Collection on Nuclear Cardiology
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Summary:Purpose of Review The aim of this review is to provide an update on quantification of myocardial blood flow (MBF) with positron emission tomography (PET) imaging. Technical and clinical aspects of flow quantification with PET are reviewed. Recent Findings The diagnostic and prognostic values of myocardial flow quantification have been established in numerous studies and in various populations. MBF quantification has also shown itself to be particularly useful in the assessment of coronary microvascular dysfunction and in evaluation of cardiac allograft vasculopathy. Overall, myocardial flow reserve (MFR) and hyperemic MBF can lead to improved risk stratification by providing information complementary to that of other markers of disease severity, such as fractional flow reserve. Summary Flow quantification enhances MPI’s ability to detect both significant epicardial disease and microvascular dysfunction. With recent technological and methodological advances, flow quantification with PET is no longer restricted to cyclotron-equipped academic centers.
ISSN:1523-3782
1534-3170
DOI:10.1007/s11886-019-1096-x