Lipid Mobilization in X-Irradiated Rabbits

The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty aci...

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Bibliographic Details
Published in:Radiation research 1961-06, Vol.14 (6), p.760-766
Main Authors: Elko, E. E., Di Luzio, N. R.
Format: Article
Language:English
Subjects:
Animals
BIOLOGY AND MEDICINE
Blood lipids
BLOOD PLASMA
Body fat
Braking radiation
CHOLESTEROL
Cholesterols
FATTY ACIDS
LETHAL DOSE
Lipid Metabolism
Lipid Mobilization
LIPIDS
Lipoproteins
Liver
Nonesterified fatty acids
Old Medline
ORGANIC ACIDS
QUANTITY RATIO
RABBITS
Radiation Effects
RADIATION INJURIES
STEROIDS
Triglycerides
X RADIATION
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Summary:The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty acid response. Plasma phospholipid, free and ester cholesterol, and triglycerides were significantly increased after x irradiation. However, plasma free fatty acids were unaltered. Finally, a similar degree of lipid depletion from the adipose depot was noted in both control and x-irradiated animals, denoting that increased peripheral lipid mobilization was not a factor in the etiology of postirradiation hyperlipemia.
ISSN:0033-7587
1938-5404
DOI:10.2307/3571016