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Lipid Mobilization in X-Irradiated Rabbits
The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty aci...
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Published in: | Radiation research 1961-06, Vol.14 (6), p.760-766 |
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creator | Elko, E. E. Di Luzio, N. R. |
description | The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty acid response. Plasma phospholipid, free and ester cholesterol, and triglycerides were significantly increased after x irradiation. However, plasma free fatty acids were unaltered. Finally, a similar degree of lipid depletion from the adipose depot was noted in both control and x-irradiated animals, denoting that increased peripheral lipid mobilization was not a factor in the etiology of postirradiation hyperlipemia. |
doi_str_mv | 10.2307/3571016 |
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E. ; Di Luzio, N. R.</creator><creatorcontrib>Elko, E. E. ; Di Luzio, N. R. ; Univ. of Tennessee Medical Units, Memphis</creatorcontrib><description>The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty acid response. Plasma phospholipid, free and ester cholesterol, and triglycerides were significantly increased after x irradiation. However, plasma free fatty acids were unaltered. Finally, a similar degree of lipid depletion from the adipose depot was noted in both control and x-irradiated animals, denoting that increased peripheral lipid mobilization was not a factor in the etiology of postirradiation hyperlipemia.</description><identifier>ISSN: 0033-7587</identifier><identifier>EISSN: 1938-5404</identifier><identifier>DOI: 10.2307/3571016</identifier><identifier>PMID: 13726403</identifier><language>eng</language><publisher>United States: Academic Press, Inc</publisher><subject>Animals ; BIOLOGY AND MEDICINE ; Blood lipids ; BLOOD PLASMA ; Body fat ; Braking radiation ; CHOLESTEROL ; Cholesterols ; FATTY ACIDS ; LETHAL DOSE ; Lipid Metabolism ; Lipid Mobilization ; LIPIDS ; Lipoproteins ; Liver ; Nonesterified fatty acids ; Old Medline ; ORGANIC ACIDS ; QUANTITY RATIO ; RABBITS ; Radiation Effects ; RADIATION INJURIES ; STEROIDS ; Triglycerides ; X RADIATION</subject><ispartof>Radiation research, 1961-06, Vol.14 (6), p.760-766</ispartof><rights>Copyright 1961 Academic Press Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-d07fb2960d91cf33bbd3410a33c9c82fb0264efced1d923958e3a6ddc3e3f3843</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3571016$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3571016$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,780,784,885,27923,27924,58237,58470</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13726403$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/4047868$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Elko, E. E.</creatorcontrib><creatorcontrib>Di Luzio, N. R.</creatorcontrib><creatorcontrib>Univ. of Tennessee Medical Units, Memphis</creatorcontrib><title>Lipid Mobilization in X-Irradiated Rabbits</title><title>Radiation research</title><addtitle>Radiat Res</addtitle><description>The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty acid response. Plasma phospholipid, free and ester cholesterol, and triglycerides were significantly increased after x irradiation. However, plasma free fatty acids were unaltered. Finally, a similar degree of lipid depletion from the adipose depot was noted in both control and x-irradiated animals, denoting that increased peripheral lipid mobilization was not a factor in the etiology of postirradiation hyperlipemia.</description><subject>Animals</subject><subject>BIOLOGY AND MEDICINE</subject><subject>Blood lipids</subject><subject>BLOOD PLASMA</subject><subject>Body fat</subject><subject>Braking radiation</subject><subject>CHOLESTEROL</subject><subject>Cholesterols</subject><subject>FATTY ACIDS</subject><subject>LETHAL DOSE</subject><subject>Lipid Metabolism</subject><subject>Lipid Mobilization</subject><subject>LIPIDS</subject><subject>Lipoproteins</subject><subject>Liver</subject><subject>Nonesterified fatty acids</subject><subject>Old Medline</subject><subject>ORGANIC ACIDS</subject><subject>QUANTITY RATIO</subject><subject>RABBITS</subject><subject>Radiation Effects</subject><subject>RADIATION INJURIES</subject><subject>STEROIDS</subject><subject>Triglycerides</subject><subject>X RADIATION</subject><issn>0033-7587</issn><issn>1938-5404</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1961</creationdate><recordtype>article</recordtype><recordid>eNp10F1LwzAUBuAgiptT_AdSRBSEatLTNsmlDD8GE0EUvAv5KmZ0zUyyC_31drTglVeHAw_v4bwInRJ8UwCmt1BRgkm9h6aEA8urEpf7aIoxQE4rRifoKMYV7ndS80M0IUCLusQwRddLt3Eme_bKte5HJue7zHXZR74IQRonkzXZq1TKpXiMDhrZRnsyzhl6f7h_mz_ly5fHxfxumWuAKuUG00YVvMaGE90AKGWgJFgCaK5Z0Sjcn7aNtoYYXgCvmAVZG6PBQgOshBk6H3J9TE5E7ZLVn9p3ndVJ9I9RVrMeXQ5oE_zX1sYk1i5q27ays34bBStq3kfv4NUAdfAxBtuITXBrGb4FwWLXnRi76-XZGLlVa2v-3FhWDy4GsIrJh39zfgEl_3Gu</recordid><startdate>19610601</startdate><enddate>19610601</enddate><creator>Elko, E. E.</creator><creator>Di Luzio, N. R.</creator><general>Academic Press, Inc</general><general>Radiation Research Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19610601</creationdate><title>Lipid Mobilization in X-Irradiated Rabbits</title><author>Elko, E. E. ; Di Luzio, N. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-d07fb2960d91cf33bbd3410a33c9c82fb0264efced1d923958e3a6ddc3e3f3843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1961</creationdate><topic>Animals</topic><topic>BIOLOGY AND MEDICINE</topic><topic>Blood lipids</topic><topic>BLOOD PLASMA</topic><topic>Body fat</topic><topic>Braking radiation</topic><topic>CHOLESTEROL</topic><topic>Cholesterols</topic><topic>FATTY ACIDS</topic><topic>LETHAL DOSE</topic><topic>Lipid Metabolism</topic><topic>Lipid Mobilization</topic><topic>LIPIDS</topic><topic>Lipoproteins</topic><topic>Liver</topic><topic>Nonesterified fatty acids</topic><topic>Old Medline</topic><topic>ORGANIC ACIDS</topic><topic>QUANTITY RATIO</topic><topic>RABBITS</topic><topic>Radiation Effects</topic><topic>RADIATION INJURIES</topic><topic>STEROIDS</topic><topic>Triglycerides</topic><topic>X RADIATION</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elko, E. E.</creatorcontrib><creatorcontrib>Di Luzio, N. R.</creatorcontrib><creatorcontrib>Univ. of Tennessee Medical Units, Memphis</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>Radiation research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elko, E. E.</au><au>Di Luzio, N. R.</au><aucorp>Univ. of Tennessee Medical Units, Memphis</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lipid Mobilization in X-Irradiated Rabbits</atitle><jtitle>Radiation research</jtitle><addtitle>Radiat Res</addtitle><date>1961-06-01</date><risdate>1961</risdate><volume>14</volume><issue>6</issue><spage>760</spage><epage>766</epage><pages>760-766</pages><issn>0033-7587</issn><eissn>1938-5404</eissn><abstract>The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty acid response. Plasma phospholipid, free and ester cholesterol, and triglycerides were significantly increased after x irradiation. However, plasma free fatty acids were unaltered. Finally, a similar degree of lipid depletion from the adipose depot was noted in both control and x-irradiated animals, denoting that increased peripheral lipid mobilization was not a factor in the etiology of postirradiation hyperlipemia.</abstract><cop>United States</cop><pub>Academic Press, Inc</pub><pmid>13726403</pmid><doi>10.2307/3571016</doi><tpages>7</tpages></addata></record> |
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ispartof | Radiation research, 1961-06, Vol.14 (6), p.760-766 |
issn | 0033-7587 1938-5404 |
language | eng |
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subjects | Animals BIOLOGY AND MEDICINE Blood lipids BLOOD PLASMA Body fat Braking radiation CHOLESTEROL Cholesterols FATTY ACIDS LETHAL DOSE Lipid Metabolism Lipid Mobilization LIPIDS Lipoproteins Liver Nonesterified fatty acids Old Medline ORGANIC ACIDS QUANTITY RATIO RABBITS Radiation Effects RADIATION INJURIES STEROIDS Triglycerides X RADIATION |
title | Lipid Mobilization in X-Irradiated Rabbits |
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